ArticleDiseases (Basel, Switzerland)2026
The Impact of Antithrombotic Therapy on Bleeding Complications in Percutaneous Liver Biopsy: Are the Withdrawal Criteria of Antithrombotic Agents in Japan Gastroenterological Endoscopy Society Guidelines for Gastroenterological Endoscopy Useful?
Article in Diseases (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundBleeding is the most important complication of percutaneous liver biopsy. However, there are many unknowns regarding the management of antithrombotic agents in percutaneous liver biopsy. We investigated whether percutaneous liver biopsy could be performed safely by withdrawal of antithrombotic agents in accordance with the criteria of gastroenterological endoscopy guidelines.
methodsA retrospective study was conducted on patients who underwent percutaneous liver biopsy. Antithrombotic agents were discontinued in accordance with the withdrawal criteria in the Japan Gastroenterological Endoscopy Society guidelines for gastroenterological endoscopy.
resultsA total of 630 cases were enrolled, including 64 cases receiving antithrombotic therapy. Bleeding complications occurred in 6.7% of cases with antithrombotic therapy and 2.1% of patients without antithrombotic therapy, with no significant difference between the two groups (
conclusionsThis study suggests that percutaneous liver biopsy may be performed safely in cases receiving antithrombotic therapy by discontinuation of antithrombotic agents in accordance with the withdrawal criteria of Japan Gastroenterological Endoscopy Society guidelines for gastroenterological endoscopy.
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