Evidence map›Paper›PMID 42346253›Full record

ArticleCurrent oncology (Toronto, Ont.)2026

Gestational Trophoblastic Neoplasia Following Hydatidiform Mole and Non-Molar Pregnancy: Clinical and Prognostic Features from a 40-Year Cohort Study at a Reference Center in Southern Brazil.

Elza Maria Hartmann Uberti, Lidia Rosi de Freitas Medeiros, Rodrigo Bernardes Cardoso, Eduardo Silveira, Cassiano Burman Patias, Carlos Eduardo Dos Santos Filho, Rosilene Jara Reis, Josenel Maria Barcelos Copetti, Jose Pio Furtado

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In one paragraph

Article in Current oncology (Toronto, Ont.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Elza Maria Hartmann UbertiGestational Trophoblastic Disease Center, Department of Obstetrics and Gynecology, Irmandade Santa Casa de Misericórdia de Porto Alegre, Porto Alegre 90035-074, RS, Brazil.ORCID 0009-0007-3754-473X
Lidia Rosi de Freitas MedeirosGestational Trophoblastic Disease Center, Department of Obstetrics and Gynecology, Irmandade Santa Casa de Misericórdia de Porto Alegre, Porto Alegre 90035-074, RS, Brazil.ORCID 0000-0002-9563-000X
Rodrigo Bernardes CardosoGestational Trophoblastic Disease Center, Department of Obstetrics and Gynecology, Irmandade Santa Casa de Misericórdia de Porto Alegre, Porto Alegre 90035-074, RS, Brazil.
Eduardo SilveiraGestational Trophoblastic Disease Center, Department of Obstetrics and Gynecology, Irmandade Santa Casa de Misericórdia de Porto Alegre, Porto Alegre 90035-074, RS, Brazil.
Cassiano Burman PatiasGestational Trophoblastic Disease Center, Department of Obstetrics and Gynecology, Irmandade Santa Casa de Misericórdia de Porto Alegre, Porto Alegre 90035-074, RS, Brazil.ORCID 0009-0002-9927-3246
Carlos Eduardo Dos Santos FilhoGestational Trophoblastic Disease Center, Department of Obstetrics and Gynecology, Irmandade Santa Casa de Misericórdia de Porto Alegre, Porto Alegre 90035-074, RS, Brazil.
Rosilene Jara ReisGestational Trophoblastic Disease Center, Department of Obstetrics and Gynecology, Irmandade Santa Casa de Misericórdia de Porto Alegre, Porto Alegre 90035-074, RS, Brazil.
Josenel Maria Barcelos CopettiGestational Trophoblastic Disease Center, Department of Obstetrics and Gynecology, Irmandade Santa Casa de Misericórdia de Porto Alegre, Porto Alegre 90035-074, RS, Brazil.
Jose Pio FurtadoGestational Trophoblastic Disease Center, Department of Obstetrics and Gynecology, Irmandade Santa Casa de Misericórdia de Porto Alegre, Porto Alegre 90035-074, RS, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGestational trophoblastic neoplasia (GTN) is rare but highly curable. This study compared clinical characteristics and outcomes between molar and non-molar disease.

methodsThis retrospective cohort included 550 patients at a Brazilian reference center (1985-2025). Survival was assessed using Kaplan-Meier methods. Multivariable analyses included Poisson and Cox regression models.

resultsMolar GTN comprised 86% of cases. Non-molar GTN (14%) presented with more advanced FIGO stages, higher WHO risk scores, and more metastases (

conclusionsAlthough non-molar GTN presents with more aggressive clinical features, survival outcomes appear to be primarily driven by baseline disease severity rather than GTN subtype itself.

Indexed as

Gestational Trophoblastic DiseaseHydatidiform MoleUterine NeoplasmsAdultBrazilCohort StudiesFemaleHumansPregnancyPrognosisRetrospective Studieschoriocarcinomagestational trophoblastic neoplasiaprognosisreference centersurvival

Identifiers

PMID42346253
PMCPMC13298583

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.