Evidence map›Paper›PMID 42346237›Full record

ArticleCurrent oncology (Toronto, Ont.)2026

Salvage Radiotherapy in Isolated Locoregional Recurrence of Pancreatic Adenocarcinoma Post-Radical Surgical Resection: Prudent or Pointless? A Retrospective Comparative Analysis.

Colin Faulkner, Ayah Erjan, Sara Mheid, Michael Yan, Chaya Ganor Shwaartz, Erica Tsang, Sangeetha Kalimuthu, Teodor Stanescu, Ali Hosni, Aruz Mesci

Abstract readComparative Study
In one paragraph

Article in Current oncology (Toronto, Ont.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Colin FaulknerRadiation Medicine Program, Princess Margaret Cancer Centre, Toronto, ON M5G 2C4, Canada.
Ayah ErjanRadiation Medicine Program, Princess Margaret Cancer Centre, Toronto, ON M5G 2C4, Canada.ORCID 0000-0002-1567-3182
Sara MheidRadiation Medicine Program, Princess Margaret Cancer Centre, Toronto, ON M5G 2C4, Canada.
Michael YanRadiation Medicine Program, Princess Margaret Cancer Centre, Toronto, ON M5G 2C4, Canada.
Chaya Ganor ShwaartzDepartment of Surgery, University of Toronto, Toronto, ON M5T 1P5, Canada.
Erica TsangMedical Oncology, Princess Margaret Cancer Centre, University of Toronto, Toronto, ON M5G 2M9, Canada.
Sangeetha KalimuthuLaboratory Medicine Program, Princess Margaret Cancer Centre, Toronto, ON M5G 2C4, Canada.
Teodor StanescuRadiation Medicine Program, Princess Margaret Cancer Centre, Toronto, ON M5G 2C4, Canada.
Ali HosniRadiation Medicine Program, Princess Margaret Cancer Centre, Toronto, ON M5G 2C4, Canada.
Aruz MesciRadiation Medicine Program, Princess Margaret Cancer Centre, Toronto, ON M5G 2C4, Canada.ORCID 0000-0002-8327-794X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Isolated Locoregionally Recurrent Pancreatic Adenocarcinoma (ILRPA) accounts for 25-30% of recurrences after radical resection, yet the role of salvage radiation (RT) in this setting remains controversial due to limited data. We aimed to evaluate the impact of salvage RT on survival outcomes compared with non-salvage RT in patients with ILRPA. We retrospectively analyzed data of patients with ILRPA post-radical resection treated at our centre between 2012 and 2021. Patients were categorized into two cohorts based on whether salvage RT was administered post-recurrence. Patients who received a minimum of 30 Gy in 10 fractions (BED

Indexed as

AdenocarcinomaNeoplasm Recurrence, LocalPancreatic NeoplasmsSalvage TherapyAdultAgedAged, 80 and overChemotherapy, AdjuvantFemaleFollow-Up StudiesHumansMaleMiddle AgedPalliative CarePancreatectomyProgression-Free Survivallocoregional recurrencepancreatic cancerradiotherapy

Identifiers

PMID42346237
PMCPMC13298439

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.