Evidence map›Paper›PMID 42346139›Full record

ArticleCells2026

Combustion and Heated Tobacco Cigarettes, but Not E-Cigarettes, Impair Aquaporin-Dependent H

Giorgia Senise, Francesca Bodega, Cristina Porta, Umberto Laforenza

Abstract read
In one paragraph

Article in Cells, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Giorgia SeniseHuman Physiology Unit, Department of Molecular Medicine, University of Pavia, 27100 Pavia, Italy.
Francesca BodegaDipartimento di Fisiopatologia Medico-Chirurgica e dei Trapianti, Università degli Studi di Milano, 20133 Milan, Italy.ORCID 0000-0003-4231-4916
Cristina PortaDipartimento di Fisiopatologia Medico-Chirurgica e dei Trapianti, Università degli Studi di Milano, 20133 Milan, Italy.ORCID 0000-0003-4674-9044
Umberto LaforenzaHuman Physiology Unit, Department of Molecular Medicine, University of Pavia, 27100 Pavia, Italy.ORCID 0000-0003-2951-5983

Funding

DDepartment of Molecular Medicine of the University of Pavia Dipartimenti di Eccellenza (2023-2028)
6 · The paper itself

Abstract

Cigarette smoke is a major inducer of oxidative stress, promoting reactive oxygen species (ROS) accumulation and contributing to the pathogenesis of chronic obstructive pulmonary disease (COPD) and lung cancer. Heated tobacco products (HTP) and e-cigarettes are promoted as reduced-risk alternatives; however, their impact on cellular redox regulation remains unclear. Here, we investigated the effects of conventional cigarette smoke extract (CSE), HTP, and e-cigarette extracts on hydrogen peroxide (H

Indexed as

AquaporinsElectronic Nicotine Delivery SystemsHot TemperatureHydrogen PeroxideTobacco ProductsCatalaseCell LineGlutathione PeroxidaseHumansOxidative StressPermeabilityReactive Oxygen SpeciesSuperoxide DismutaseAquaporinsCatalaseGlutathione PeroxidaseHydrogen PeroxideReactive Oxygen SpeciesSuperoxide Dismutasecatalasee-cigaretteglutathione peroxidaseheated tobaccohydrogen peroxideHyPer7 biosensoroxidative stressperoxiporinssuperoxide dismutasetraditional cigarette smoke

Identifiers

PMID42346139
PMCPMC13297388

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.