Evidence map›Paper›PMID 42346061›Full record

ArticleInfectious disease reports2026

Salvage Treatment of Ventilator-Associated Pneumonia Using Sulbactam-Durlobactam in a Preterm Neonate: A Case Report.

Suzana Zivojinovic, Tijana Prodanovic, Nikola Prodanovic, Rasa Medovic, Milica Cekerevac, Dragana Savic, Bojana Markovic, Slobodan Jankovic

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Infectious disease reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Suzana ZivojinovicDepartment of Pediatrics, Faculty of Medical Sciences, University of Kragujevac, 34000 Kragujevac, Serbia.ORCID 0000-0002-6844-2150
Tijana ProdanovicDepartment of Pediatrics, Faculty of Medical Sciences, University of Kragujevac, 34000 Kragujevac, Serbia.ORCID 0000-0002-7399-2480
Nikola ProdanovicUniversity Clinical Center Kragujevac, 34000 Kragujevac, Serbia.ORCID 0000-0003-0760-3931
Rasa MedovicDepartment of Pediatrics, Faculty of Medical Sciences, University of Kragujevac, 34000 Kragujevac, Serbia.
Milica CekerevacDepartment of Pediatrics, Faculty of Medical Sciences, University of Kragujevac, 34000 Kragujevac, Serbia.ORCID 0009-0006-9413-4799
Dragana SavicDepartment of Pediatrics, Faculty of Medical Sciences, University of Kragujevac, 34000 Kragujevac, Serbia.
Bojana MarkovicDepartment of Pediatrics, Faculty of Medical Sciences, University of Kragujevac, 34000 Kragujevac, Serbia.ORCID 0009-0001-3179-6043
Slobodan JankovicUniversity Clinical Center Kragujevac, 34000 Kragujevac, Serbia.ORCID 0000-0002-1519-8828

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVentilator-associated pneumonia (VAP) is a leading cause of nosocomial infections in neonatal intensive care units (NICUs) and is associated with significant morbidity, mortality, and prolonged hospitalization, particularly in preterm neonates. Management is complicated by the emergence of multidrug-resistant (MDR) and extensively drug-resistant (XDR) pathogens, with very limited evidence supporting the use of reserve antibiotics in this population. CASE PRESENTATION: We report a male neonate born at 25 weeks of gestation (birth weight 740 g) who developed severe VAP caused by XDR

conclusionsThis case highlights the therapeutic challenges of XDR infections in extremely preterm neonates and suggests that sulbactam-durlobactam may represent a viable salvage treatment option. Further pharmacokinetic and clinical studies are needed to establish optimal dosing and safety in the neonatal population.

Indexed as

Acinetobacter baumanniiceftazidime–avibactammultidrug resistanceneonatal intensive care unitpreterm neonatesulbactam–durlobactamventilator-associated pneumonia

Identifiers

PMID42346061
PMCPMC13299867

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.