Evidence map›Paper›PMID 42345806›Full record

ArticleBiology2026

Targeting the Cerebellar Circuit: How Exercise Intervention Reshapes White Matter Networks to Alleviate Autism Symptoms.

Kelong Cai, Yifan Shi, Kai Qi, Yufei Liu, Zhimei Liu, Aiguo Chen

Abstract read
In one paragraph

Article in Biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kelong CaiSchool of Sport and Brain Health, Nanjing Sport Institute, Nanjing 210014, China.ORCID 0009-0006-3908-7176
Yifan ShiSchool of Sport and Brain Health, Nanjing Sport Institute, Nanjing 210014, China.ORCID 0000-0002-1949-4202
Kai QiDepartment of Physical Education, Gdansk University of Physical Education and Sport, 80-336 Gdansk, Poland.
Yufei LiuDepartment of Physical Education, Gdansk University of Physical Education and Sport, 80-336 Gdansk, Poland.ORCID 0000-0002-7071-3343
Zhimei LiuDepartment of Rehabilitation Medicine, The Affiliated Hospital of Yangzhou University, Yangzhou 225012, China.
Aiguo ChenSchool of Sport and Brain Health, Nanjing Sport Institute, Nanjing 210014, China.

Funding

National Social Science Fund of China 23ATY008
6 · The paper itself

Abstract

Although exercise interventions have been shown to alleviate core symptoms of Autism Spectrum Disorder (ASD), the neural mechanisms underlying these improvements, particularly those involving the White Matter Network (WMN), remain poorly understood. This study investigated the effects of a Mini-Basketball Training Program (MBTP) on core symptoms and WMN in children with ASD. This study adopted a two-site cluster-Randomized Controlled Trial (cRCT) design. Participants from two special education centers in China were randomly assigned to either an intervention group (MBTP) or a control group (CON). The participants underwent a 12-week MBTP. Core symptom assessments and a Diffusion Tensor Imaging (DTI) scan were conducted before and after the intervention. The individual WMNs were constructed using Deterministic Fiber Tracking (DFT). Graph theoretical analysis was applied to examine changes in WMN topological properties after MBTP. The MBTP significantly improved core symptoms in children with ASD, alongside the decreased normalized clustering coefficient (

Indexed as

autism spectrum disorderexercise interventionMRIrandomized controlled trialtopological propertieswhite matter network

Identifiers

PMID42345806
PMCPMC13295291

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.