Biochemical, Immunohistochemical and Behavioral Effects of Spexin in a Methimazole-Induced Hypothyroidism Rat Model.

Seda Koçak, Gülhan Ünlü, Kübra Tuğçe Kalkan, Ferhat Pektaş, Ahmet Türk

Abstract read

In one paragraph

Article in Biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Seda KoçakDepartment of Physiology, Faculty of Medicine, Kırşehir Ahi Evran University, Kırşehir 40100, Türkiye.ORCID 0000-0003-1183-4847

Gülhan ÜnlüDepartment of Pharmacology, Faculty of Medicine, Kırşehir Ahi Evran University, Kırşehir 40100, Türkiye.

Kübra Tuğçe KalkanDepartment of Embryology and Histology, Faculty of Medicine, Kırşehir Ahi Evran University, Kırşehir 40100, Türkiye.

Ferhat PektaşDepartment of Physiology, Faculty of Medicine, Kırşehir Ahi Evran University, Kırşehir 40100, Türkiye.ORCID 0000-0002-1862-9515

Ahmet TürkDepartment of Embryology and Histology, Faculty of Medicine, Adıyaman University, Kırşehir 02040, Türkiye.

Funding

Ahi Evran University TIP.A3.24.010

6 · The paper itself

Abstract

Hypothyroidism is associated with metabolic, neurobehavioral, and reproductive alterations that may involve neuroendocrine regulatory peptides. Spexin, a neuropeptide implicated in energy homeostasis, has recently attracted attention for its possible role in thyroid and reproductive axis regulation. Therefore, this study aimed to investigate the effects of spexin on neurobehavioral responses and the tissue-specific expression of irisin and KISS-1 in the cerebral cortex and testis under hypothyroid conditions. Thirty-two male

Indexed as

behaviorhypothyroidirisinkisspeptinspexin

Identifiers

PMID42345788

DOI10.3390/biology15120932

PMCPMC13295690

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.