Evidence map›Paper›PMID 42345641›Full record

Observational studyAdvances in respiratory medicine2026

Impact of Highly Effective CFTR Modulator Therapy on Physical Activity, Sleep, and Sinonasal Symptoms in Preschool Children with Cystic Fibrosis: A Prospective Single-Center Pilot Study.

Stella Schellhorn, Hanna Schmidt, Ales Janda, Doris Gülke, Monika Toth, Dorit Fabricius, Sebastian F N Bode

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Advances in respiratory medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Stella SchellhornDepartment of Pediatrics and Adolescent Medicin, Ulm University Medical Center, Ulm University, Eythstrasse 24, 89075 Ulm, Germany.
Hanna SchmidtDepartment of Pediatrics and Adolescent Medicin, Ulm University Medical Center, Ulm University, Eythstrasse 24, 89075 Ulm, Germany.
Ales JandaDepartment of Pediatrics and Adolescent Medicin, Ulm University Medical Center, Ulm University, Eythstrasse 24, 89075 Ulm, Germany.
Doris GülkeDepartment of Pediatrics and Adolescent Medicin, Ulm University Medical Center, Ulm University, Eythstrasse 24, 89075 Ulm, Germany.
Monika TothDepartment of Pediatrics and Adolescent Medicin, Ulm University Medical Center, Ulm University, Eythstrasse 24, 89075 Ulm, Germany.
Dorit FabriciusDepartment of Pediatrics and Adolescent Medicin, Ulm University Medical Center, Ulm University, Eythstrasse 24, 89075 Ulm, Germany.ORCID 0000-0002-2019-8101
Sebastian F N BodeDepartment of Pediatrics and Adolescent Medicin, Ulm University Medical Center, Ulm University, Eythstrasse 24, 89075 Ulm, Germany.ORCID 0000-0001-7217-3312

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AminophenolsBenzodioxolesCystic FibrosisCystic Fibrosis Transmembrane Conductance RegulatorExerciseIndolesPyrazolesPyridinesQuinolonesSleepChildChild, PreschoolDrug CombinationsFemaleHumansMaleAminophenolsBenzodioxolesCystic Fibrosis Transmembrane Conductance RegulatorDrug CombinationselexacaftorIndolesivacaftorPyrazolesPyridinesPyrrolidinesQuinolonestezacaftorThiophenesactigraphyactivityCFTR-modulatorcystic fibrosispreschool childrensinonasal symptomssleepwearables

Identifiers

PMID42345641
PMCPMC13296162

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.