Evidence map›Paper›PMID 42345585›Full record

ArticleJournal of bacteriology2026

DNA damage-associated vesicle production in

Darshan Chandramowli, Eva Mortier, Joni Elsmoortel, Jolien Vitse, Stijn De Waele, Stephan Stremersch, Koen Raemdonck, Kevin Braeckmans, Jan Felix, Bart Devreese

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of bacteriology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Darshan ChandramowliLaboratory of Microbiology, Department of Biochemistry and Microbiology, Ghent University, Ghent, Belgium.ORCID 0000-0001-5210-9639
Eva MortierLaboratory of Microbiology, Department of Biochemistry and Microbiology, Ghent University, Ghent, Belgium.ORCID 0009-0004-0737-2306
Joni ElsmoortelLaboratory of Microbiology, Department of Biochemistry and Microbiology, Ghent University, Ghent, Belgium.
Jolien VitseLaboratory of Microbiology, Department of Biochemistry and Microbiology, Ghent University, Ghent, Belgium.
Stijn De WaeleLaboratory of Microbiology, Department of Biochemistry and Microbiology, Ghent University, Ghent, Belgium.
Stephan StremerschLaboratory of Microbiology, Department of Biochemistry and Microbiology, Ghent University, Ghent, Belgium.
Koen RaemdonckLaboratory of General Biochemistry and Physical Pharmacy, Faculty of Pharmaceutical Sciences, Ghent University, Ghent, Belgium.
Kevin BraeckmansLaboratory of General Biochemistry and Physical Pharmacy, Faculty of Pharmaceutical Sciences, Ghent University, Ghent, Belgium.
Jan FelixUnit for Structural Biology, VIB-UGent Center for Inflammation Research and Department of Biochemistry and Microbiology, Ghent, Belgium.
Bart DevreeseLaboratory of Microbiology, Department of Biochemistry and Microbiology, Ghent University, Ghent, Belgium.ORCID 0000-0002-9764-2581

Funding

Belgian Federal Science Policy Office NanomotionFonds Wetenschappelijk Onderzoek FWO.OPR.2022.0068.01Fonds Wetenschappelijk Onderzoek G005719NWellcome TrustWellcome Trust 203141/Z/16/Z
6 · The paper itself

Abstract

In this study, we examined the effects of antibiotic-mediated DNA damage on vesiculation in a clinical strain of IMPORTANCE: In their natural environment, bacterial cells are able to communicate among themselves in multiple ways, and this communication has important implications for their ability to deal with unfavorable conditions. One key consequence is the spread of antimicrobial resistance from resistant cells to the remaining population, and such transfer can be mediated by membrane vesicles. In the highly multidrug-resistant bacterium

Indexed as

Cytoplasmic VesiclesDNA DamageEndopeptidasesStenotrophomonas maltophiliaAnti-Bacterial AgentsCiprofloxacinAnti-Bacterial AgentsCiprofloxacinendolysinEndopeptidasesantibiotic responsemembrane vesiclesphage

Identifiers

PMID42345585
PMCPMC13393414

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.