Trial reportMenopause (New York, N.Y.)2025
Processed foods in the context of a vegan diet, and changes in body weight and severe hot flashes in postmenopausal women: a secondary analysis of a randomized clinical trial.
Trial report in Menopause (New York, N.Y.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Optimal Dietary Patterns for Lower Weight Gain and Risk of Obesity Surrounding Menopause.JAMA network open · 2026Article
- Not all ultra-processed foods are created equal: a review.BMJ nutrition, prevention & health · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesA plant-based diet has been shown to reduce hot flashes, partly by weight loss. Because some plant-based foods are highly processed, this secondary analysis assessed associations between consumption of processed foods, body weight, and severe hot flashes in postmenopausal women.
methodsParticipants (N=84) were randomly assigned to a low-fat vegan diet supplemented with soybeans (n=42) or an omnivorous control group (n=42) for 12 weeks. Three-day diet records were analyzed using the Nutrition Data System for Research software; the NOVA classification was used to assess processed food consumption. A repeated measures ANOVA was used for statistical analyses.
resultsConsumption of unprocessed or minimally processed animal foods decreased in the vegan group, compared with the control group; effect size: -106 g/d (95% CI: -169 to -42); P=0.002. The reduction in consumption of unprocessed or minimally processed animal foods was associated with weight loss (r=+0.45; P<0.001) and a reduction in severe hot flashes (r=+0.31; P=0.01). Similarly, consumption of ultra-processed animal foods decreased in the vegan group by 60 g/d (95% CI: -105 to -15); P=0.004, with no significant change in the control group; effect size: -65 g/d (95% CI: -115 to -16); P=0.01. The reduction in consumption of ultra-processed animal foods was associated with weight loss (r=+0.43; P<0.001). Consumption of ultra-processed plant-based foods changed only minimally and nonsignificantly and was not associated with changes in weight or hot flash frequency.
conclusionsThese findings suggest that, in the context of a soybean-supplemented vegan diet, replacing the consumption of both unprocessed or minimally processed and ultra-processed animal foods with plant foods (regardless of the level of processing), was associated with significant weight loss and a reduction in severe hot flashes.
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