Evidence map›Paper›PMID 42344796›Full record

ArticleFrontiers in pharmacology2026

The TASK-1 and TASK-3 activator JG-C3-98 attenuates cold and mechanical responses in primary somatosensory neurons.

Pedro De-la-Torre, Miguel Valencia, Jaime Gálvez, Victoria Flores Del Pino, Ana Gómez Del Campo, Sofía Romero, Elizabeth Mendoza, Susanne Rinné, Aytug Kiper, Luis Prent and 13 more

Abstract read
In one paragraph

Article in Frontiers in pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Pedro De-la-Torre *Department of Otolaryngology - Head and Neck Surgery, Harvard Medical School and Mass Eye and Ear, Boston, MA, United States.
Miguel Valencia *Departamento de Biología, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago, Chile.
Jaime GálvezFaculty of Engineering, School of Food Engineering, Universidad del Valle, Tuluá, Colombia.
Victoria Flores Del PinoDepartamento de Biología, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago, Chile.
Ana Gómez Del CampoDepartamento de Biología, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago, Chile.
Sofía RomeroDepartamento de Biología, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago, Chile.
Elizabeth MendozaDepartamento de Biología, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago, Chile.
Susanne RinnéInstitut für Physiologie und Pathophysiologie, Philipps-Universität Marburg, Marburg, Germany.
Aytug KiperInstitut für Physiologie und Pathophysiologie, Philipps-Universität Marburg, Marburg, Germany.
Luis PrentDepartamento de Ciencias Químicas, Facultad de Ciencias Exactas, Universidad Andrés Bello, Viña del Mar, Chile.
Ariela Vergara-JaqueCenter for Bioinformatics, Simulations and Modelling, Universidad de Talca, Talca, Chile.
Yuliet MazolaCenter for Bioinformatics, Simulations and Modelling, Universidad de Talca, Talca, Chile.
Christian Olivera-FuentesLaboratorio de Fisiología Molecular, Facultad de Medicina, Universidad de Talca, Talca, Chile.
Rafael ZúñigaLaboratorio de Fisiología Molecular, Facultad de Medicina, Universidad de Talca, Talca, Chile.
José C E Márquez MontesinosCenter for Bioinformatics, Simulations and Modelling, Universidad de Talca, Talca, Chile.
Benjamín RojasCenter for Bioinformatics, Simulations and Modelling, Universidad de Talca, Talca, Chile.
Luciano PeñaCenter for Bioinformatics, Simulations and Modelling, Universidad de Talca, Talca, Chile.
Jairo QuirogaHeterocyclic Compounds Research Group, Department of Chemistry, Universidad del Valle, Cali, Colombia.
María PertusaDepartamento de Biología, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago, Chile.
Niels DecherInstitut für Physiologie und Pathophysiologie, Philipps-Universität Marburg, Marburg, Germany.
Leandro ZúñigaLaboratorio de Fisiología Molecular, Facultad de Medicina, Universidad de Talca, Talca, Chile.
Wendy GonzálezCenter for Bioinformatics, Simulations and Modelling, Universidad de Talca, Talca, Chile.
Rodolfo MadridDepartamento de Biología, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago, Chile.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

K2P channels underlie background K

Indexed as

K2P channelsnociceptive behaviorpainperipheral neuropathiespharmacology of K2P channels

Identifiers

PMID42344796
PMCPMC13286800

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.