ArticleAsian journal of transfusion science
Paws to Pause: Trends in blood donor deferral rates due antirabies vaccination following animal bite: A 4-year retrospective study from a tertiary care hospital blood center in Delhi.
Article in Asian journal of transfusion science. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Rabies viral RNA and antibody response after post-exposure prophylaxis: Implications for blood donor deferral.Tropical diseases, travel medicine and vaccines · 2026Article
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8 authors.
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Abstract
backgroundIndia faces a growing challenge of an increasing stray dog population and bite incidents, leading to donor deferrals. As incidence of bite-related deferrals is rapidly rising among the top primary causes of temporary donor deferrals, this trend poses a risk to an already constrained donor pool. Deferrals frequently lead to donor attrition, hence, understanding its impact is critical for blood supply management.
aimsTo analyze prevalence, trends, and impact of antirabies vaccination (ARV) following animal bite-related donor deferrals in a tertiary care hospital blood center in Delhi from January 2021 to April 2025. STUDY
designA retrospective observational study conducted on blood donor deferrals due to ARV. MATERIALS AND
methodsData were extracted from donor screening logs and compared with hospital emergency room/outpatient departments (ER/OPD) records of patients postexposure prophylaxis (PEP) with ARV during the same period. Trends in ARV-related deferrals were calculated and compared with % PEP-ARV cases in ER/OPD.
resultsDuring this period, 68,296 donors registered at our blood center, of whom 7094 (10.4%) were deferred for not meeting eligibility criteria. Among these, 528 (7.7%) were temporarily deferred due to ARV. The ARV-related deferral rate showed an alarming rise of 189.5% (3.8% in 2021-11% by April 2025), correlating with the rising number of PEP-ARV cases in the ER/OPD. Notably, only 1.32% of these returned for subsequent donation, indicating substantial donor attrition.
conclusionARV-related deferrals are rising and significantly impacting donor retention. Revising deferral policies, enhancing public awareness, and integrating bite surveillance with donor data are essential to maintain the blood supply and address this growing concern.
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