ReviewAsian journal of transfusion science
The role of platelet transfusion in modulating platelet indices and leukocyte dynamics in dengue fever patients.
Review in Asian journal of transfusion science. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dengue fever, a viral illness transmitted by Aedes mosquitoes, is marked by a reduction in platelet count (PLT) and changes in blood parameters, which increase the risk of complications such as hemorrhage. Platelet transfusion is frequently used to counter thrombocytopenia in dengue cases, but the precise effects on platelet indices (such as mean platelet volume [MPV] and platelet distribution width [PDW]) and leukocyte counts are still not well defined. This literature review investigates the role of platelet transfusions in modifying platelet and leukocyte dynamics in dengue patients. Studies reveal that transfusions can temporarily increase PLTs, offering short-term hemostatic stability. Changes in platelet indices post-transfusion include increased MPV and variable PDW, potentially reflecting reactive changes in the bone marrow and platelet population. Leukocyte counts show inconsistent responses, with some reports indicating a transient rise following transfusion, possibly linked to immune responses to transfused platelets. While platelet transfusion offers symptomatic relief, these findings highlight the complex interactions within the hematological system following transfusion and underscore the need for caution in transfusion practices. Further investigation is essential to delineate optimal transfusion thresholds, better predict hematological responses, and minimize potential risks associated with transfusions in dengue patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.