Evidence map›Paper›PMID 42344602›Full record

ArticleEnvironment & health (Washington, D.C.)2026

The Association between Prenatal Quaternary Ammonium Compounds (QACs) Exposure and Neonatal Birth Obesity: Insights from Epidemiology and

Yongfeng Lin, Xiangyu Liu, Chunyan Deng, Rui Zhang, Xiaozun Liu, Wenxuan Li, Liqin Wang, Jing Yang, Chuanhai Li, Mingshu Li and 4 more

Abstract read
In one paragraph

Article in Environment & health (Washington, D.C.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Yongfeng LinSchool of Public Health, The Affiliated Hospital of Qingdao University, Qingdao 266071, China.ORCID https://orcid.org/0000-0003-0307-3531
Xiangyu LiuSchool of Public Health, The Affiliated Hospital of Qingdao University, Qingdao 266071, China.
Chunyan DengSchool of Public Health, The Affiliated Hospital of Qingdao University, Qingdao 266071, China.
Rui ZhangSchool of Public Health, The Affiliated Hospital of Qingdao University, Qingdao 266071, China.
Xiaozun LiuSchool of Public Health, The Affiliated Hospital of Qingdao University, Qingdao 266071, China.
Wenxuan LiSchool of Public Health, The Affiliated Hospital of Qingdao University, Qingdao 266071, China.
Liqin WangSchool of Public Health, The Affiliated Hospital of Qingdao University, Qingdao 266071, China.
Jing YangSchool of Public Health, The Affiliated Hospital of Qingdao University, Qingdao 266071, China.
Chuanhai LiZhejiang Key Laboratory of Environment and Health of New Pollutants, School of Environment, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou 310024, China.
Mingshu LiChina CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China.
Dawei LuState Key Laboratory of Environmental Chemistry and Toxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China.ORCID https://orcid.org/0000-0002-8128-6367
Wei GaoSchool of Public Health, The Affiliated Hospital of Qingdao University, Qingdao 266071, China.ORCID https://orcid.org/0000-0001-9502-722X
Yong TianSchool of Environmental & Municipal Engineering, Qingdao University of Technology, Qingdao 266033, China.ORCID https://orcid.org/0000-0001-9936-3781
Yuxin ZhengSchool of Public Health, The Affiliated Hospital of Qingdao University, Qingdao 266071, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Quaternary ammonium compounds (QACs) are frequently used chemicals in consumer, medical, and personal care products that could be detected in blood samples from the general population. Cord blood samples are frequently employed in epidemiological studies to evaluate the links between contaminant exposure and birth outcomes. However, a significant knowledge gap persists regarding the presence of QACs in cord blood and their potential associations with birth outcomes. In this study, QACs were analyzed in 235 cord blood samples collected in a hospital in Jinan, Shandong Province, from February 2017 to January 2022. QACs were detected in the investigated cord blood samples, with total concentrations reaching up to 47.3 ng/mL. Benzylalkyldimethyl ammonium compounds (BACs) accounted for the largest proportion, with BAC-C12 and BAC-C14 being the most abundant QACs. The multiple linear regression (MLR) and Bayesian kernel machine regression (BKMR) models were developed to explore the relationships between QACs exposure and newborn birth outcomes. Results showed that BAC-C10, BAC-C16, and octyl decyldimethyl ammonium-8:10 were positively associated with birth weight and ponderal index (

Indexed as

environmental obesogensnewborn obesityperoxisome proliferator-activated receptor gamma (PPARγ)prenatal exposurequaternary ammonium compounds

Identifiers

PMID42344602
PMCPMC13288226

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