Evidence map›Paper›PMID 42344597›Full record

ArticleEnvironment & health (Washington, D.C.)2026

Risk Assessment of PFAS-Induced Male Reproductive Toxicity: A Comprehensive Evaluation Using the TRAEC Strategy.

Xiaoyu Xu, Ziye Xia, Junyao Luo, Weiyue Hu, Yujie Liu, Xuan Ma, Xu Wang, Quanquan Guan, Di Wu, Aizhen Wang and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Environment & health (Washington, D.C.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Xiaoyu XuKey Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing 211166, China.
Ziye XiaKey Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing 211166, China.
Junyao LuoKey Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing 211166, China.
Weiyue HuKey Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing 211166, China.
Yujie LiuKey Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing 211166, China.
Xuan MaThe Affiliated Wuxi Center for Disease Control and Prevention of Nanjing Medical University, Wuxi Center for Disease Control and Prevention, Wuxi Medical Center, Nanjing Medical University, Wuxi 214023, China.
Xu WangClinical Medical Research Center, Children's Hospital of Nanjing Medical University, Nanjing 210008, China.
Quanquan GuanKey Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing 211166, China.
Di WuKey Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing 211166, China.
Aizhen WangThe Affiliated Wuxi Center for Disease Control and Prevention of Nanjing Medical University, Wuxi Center for Disease Control and Prevention, Wuxi Medical Center, Nanjing Medical University, Wuxi 214023, China.
Yankai XiaKey Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing 211166, China.ORCID https://orcid.org/0000-0003-0484-4035

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Male fertility has declined rapidly in recent decades, a trend coinciding with increased environmental exposure pressures. Among these, perfluorinated and polyfluorinated alkyl substances (PFAS) have been reported to exert male reproductive toxicity, yet comparative risks across individual PFAS remain unclear. In this study, we employed an innovative systematic review strategy, the Targeted Risk Assessment of Environmental Chemicals (TRAEC) strategy, integrating all available evidence from 25 epidemiological studies, 75

Indexed as

male reproductive healthPFASrisk assessmentsex steroid hormone levelssperm quality

Identifiers

PMID42344597
PMCPMC13288235

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.