Evidence map›Paper›PMID 42344533›Full record

ArticleACG case reports journal2026

Drug-Induced Liver Injury Associated With an Over-The-Counter Supplement.

David Pearose, Esteban Perez Montoya, John Gutierrez, John Cuenca, Rodolfo Singleterry, Ashequlla Qudratulla, Anish Saikumar, Mohammad Housini

Abstract readCase Reports
In one paragraph

Article in ACG case reports journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

David PearoseDepartment of Internal Medicine, University Health San Antonio, San Antonio, TX.
Esteban Perez MontoyaGraduate School of Biomedical Sciences, UT Health San Antonio, San Antonio, TX.ORCID https://orcid.org/0000-0003-1024-3260
John GutierrezDepartment of Internal Medicine, Texas Institute for Graduate Medical Education and Research, San Antonio, TX.
John CuencaDepartment of Internal Medicine, Texas Institute for Graduate Medical Education and Research, San Antonio, TX.
Rodolfo SingleterryDepartment of Internal Medicine, Texas Institute for Graduate Medical Education and Research, San Antonio, TX.
Ashequlla QudratullaDepartment of Internal Medicine, Texas Institute for Graduate Medical Education and Research, San Antonio, TX.
Anish SaikumarDepartment of Internal Medicine, Texas Institute for Graduate Medical Education and Research, San Antonio, TX.
Mohammad HousiniDepartment of Pharmacology and Neuroscience, UNT Health Fort Worth, College of Biomedical and Translational Sciences, Fort Worth, TX.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Use of herbal and dietary supplements has increased worldwide, with a parallel rise in herbal and dietary supplement-associated liver injury in the United States. Limited regulation and inconsistent labeling complicate diagnosis. We report a 65-year-old woman who developed severe hepatocellular drug-induced liver injury after chronic ingestion of Artri King, an unregulated product previously flagged for undisclosed pharmaceutical ingredients, including diclofenac and corticosteroids. Evaluation excluded viral, autoimmune, and metabolic etiologies. Liver biopsy demonstrated a hepatocellular injury pattern, and liver tests improved after discontinuation. This case underscores the need for routine supplement screening and stronger regulatory oversight.

Indexed as

drug-induced liver injuryhepatotoxicityherbal and dietary supplementsNSAID adulterationtoxic hepatitis

Identifiers

PMID42344533
PMCPMC13290189

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.