ReviewFrontiers in genetics2026
The relationship between DNA damage and repair and the occurrence and development of disease.
Review in Frontiers in genetics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
5 authors.
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Abstract
DNA damage can lead to the development of diseases such as tumors. To counteract this, organisms have evolved various repair mechanisms targeting different types of damage. In eukaryotes, there are four main types of DNA repair: nucleotide excision repair (NER), base excision repair (BER), mismatch repair (MMR), and double-strand break repair (DSB repair). NER can remove large fragments of DNA damage, BER can repair damage to individual bases, MMR is used to repair base mismatch, while DSB repair includes two mechanisms: non-homologous end joining (NHEJ) and homologous recombination (HR). NHEJ directly connects the broken ends without a template, while HR uses intact sister chromatids as repair templates. Studying DNA damage and repair mechanisms can pave the way for developing new clinical drugs.
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