ArticleAnnals of surgery open : perspectives of surgical history, education, and clinical approaches2026
Revascularization for Coronary Artery Disease and Mitral Regurgitation: A Systematic Review and Meta-analysis.
Article in Annals of surgery open : perspectives of surgical history, education, and clinical approaches, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
6 authors.
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Abstract
Background: Coronary artery disease (CAD) and ischemic mitral regurgitation (IMR) commonly co-exist, yet the optimal intervention for these patients is unclear. Herein, we perform a systematic review and meta-analysis comparing the outcomes of patients with multivessel CAD and IMR undergoing coronary artery bypass grafting (CABG) or percutaneous coronary intervention (PCI). Methods: PubMed and Embase were systematically searched for articles comparing outcomes of patients with CAD and IMR undergoing revascularization with CABG or PCI, with or without concomitant mitral valve interventions. Thousand two hundred eighty-five studies were identified and 8 were included in this review after full text review. The primary outcome of this study was mortality, and secondary outcomes included myocardial infarction, stroke, heart failure hospitalizations, and residual or recurrent mitral regurgitation. Results: Pooled analyses identified no significant differences in long-term mortality [odds ratio (OR): 1.13, 95% confidence interval (CI): 0.77-1.68, Conclusion: This systematic review and meta-analysis suggested lower rates of long-term mortality and heart failure hospitalizations for CABG compared to PCI. CABG remains preferrable for patients with acceptable surgical risk, multivessel CAD, and IMR.
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