Evidence map›Paper›PMID 42344467›Full record

ArticleAnnals of surgery open : perspectives of surgical history, education, and clinical approaches2026

Short-Term Functional Trajectories After Surgery in Older Adults: National Patterns of Loss and Recovery in 436,471 Patients.

Dany Y Matar, Charbel G Saad, Anahita Nimbalkar, Sue-Yan Lai, Thomas Schaschinger, Sarah Friedrich, Jasmin Rühl, Samuel Knoedler, Leonard Knoedler, Steffen Koerdt and 6 more

Abstract read
In one paragraph

Article in Annals of surgery open : perspectives of surgical history, education, and clinical approaches, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

16 authors.

Dany Y MatarFrom the Division of Plastic Surgery, Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
Charbel G SaadDepartment of Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine, Baltimore, MD.
Anahita NimbalkarDepartment of Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine, Baltimore, MD.
Sue-Yan LaiDepartment of Acute Medicine, Royal Free Hospital, London, UK.
Thomas SchaschingerBG Klinik Ludwigshafen, Department of Hand, Plastic, and Reconstructive Surgery, Burn Center at Heidelberg University, Ludwigshafen, Germany.
Sarah FriedrichDepartment of Mathematical Statistics and Artificial Intelligence in Medicine, University of Augsburg, Augsburg, Germany.
Jasmin RühlDepartment of Mathematical Statistics and Artificial Intelligence in Medicine, University of Augsburg, Augsburg, Germany.
Samuel KnoedlerFrom the Division of Plastic Surgery, Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
Leonard KnoedlerDepartment of Oral and Maxillofacial Surgery, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany.
Steffen KoerdtDepartment of Oral and Maxillofacial Surgery, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany.
Carsten RendenbachDepartment of Oral and Maxillofacial Surgery, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany.
Leila Harhaus-WaehnerDepartment of Hand, Replantation, and Microsurgery BG Klinikum Unfallkrankenhaus Berlin and Chair of Hand, Replantation, and Microsurgery at the Charité University Medicine Berlin, Berlin, Germany.
Max HeilandDepartment of Oral and Maxillofacial Surgery, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany.
Dennis P OrgillFrom the Division of Plastic Surgery, Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
Gabriel HundeshagenBG Klinik Ludwigshafen, Department of Hand, Plastic, and Reconstructive Surgery, Burn Center at Heidelberg University, Ludwigshafen, Germany.
Adriana C PanayiDepartment of Cranio-Maxillofacial and Oral Surgery, University Hospital Zurich, University of Zurich, Zurich, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To characterize short-term functional trajectories and identify risk factors for loss and recovery of independence among older surgical patients at a national level. Background: As the surgical population ages, frailty increasingly influences outcomes beyond mortality. Short-term postoperative functional independence is a key patient-centered outcome with long-term implications, yet national data across surgical specialties remain limited. Methods: We conducted a retrospective cohort study using the 2022-2024 American College of Surgeons National Surgical Quality Improvement Program database, including all patients aged ≥75 years. Patients were categorized by functional trajectory from admission to 30 days postdischarge: maintenance of independence, loss of independence (LOI), maintenance of dependence, or gain of independence (GOI). Multivariable logistic regression identified independent factors associated with LOI among baseline-independent patients, and with GOI among baseline-dependent patients. Prespecified subgroup analyses assessed effect modification by dementia, age, frailty (mFI-5 score), surgical specialty, surgical approach, urgency, and setting. Results: Among 436,471 patients, 28.2% of baseline-independent adults experienced LOI, while 5.6% of baseline-dependent patients experienced GOI. LOI rates increased stepwise with age and frailty and were strongly associated with frailty, recent falls, preoperative sepsis, higher American Society of Anesthesiologists class, urgent/emergent surgery, inpatient setting, and open surgical approaches. LOI was associated with markedly higher postoperative mortality, prolonged hospitalization, delirium, sepsis, ventilator dependence, and nonhome discharge. Dementia was independently associated with LOI risk and inversely with GOI risk across nearly all subgroups. Conclusions: Short-term LOI is common among adults aged ≥75 years and represents a powerful marker of adverse postoperative complications. Dementia and perioperative acuity are dominant associated factors of short-term functional trajectory, while short-term recovery of independence is rare. Findings suggest that short-term functional outcomes should be incorporated into preoperative risk stratification, shared decision-making, and perioperative care pathways for older adults.

Indexed as

big dataloss of independenceoutcomesquality improvementsurgery

Identifiers

PMID42344467
PMCPMC13290161

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.