Evidence map›Paper›PMID 42344441›Full record

ArticleCurrent opinion in physiology2026

Circadian physiology changes with aging: age is just a number, but circadian physiology keeps time.

Natalie J Bohmke, Karyn A Esser

Abstract read
In one paragraph

Article in Current opinion in physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Natalie J BohmkeDepartment of Physiology and Aging, University of Florida, Gainesville, FL 32608, USA.
Karyn A EsserDepartment of Physiology and Aging, University of Florida, Gainesville, FL 32608, USA.

Funding

Study of Muscle, Mobility and Aging: SOMMA2R01AG059416 · NIA · CALIFORNIA PACIFIC MED CTR RES INSTITUTE · PI STEVEN RON CUMMINGS, Peggy Mannen Cawthon · 2018 to 2026
$70.3M
University of Florida Older Americans Independence Center (OAIC)P30AG028740 · NIA · UNIVERSITY OF FLORIDA · PI Karyn A Esser, Todd Manini · 2007 to 2026
$22.8M
Multidimensional predictive modeling to understand mechanisms of exercise response heterogeneity in older adultsR01AG089192 · NIA · FLORIDA INSTITU /HUMAN/MACHINE COGNITION · PI MARCAS M BAMMAN, Sue C Bodine · 2024 to 2026
$4.5M
Translational Research Training on Aging and Mobility (TRAM)T32AG062728 · NIA · UNIVERSITY OF FLORIDA · PI Todd Manini · 2020 to 2026
$2.0M
NIA NIH HHS P30 AG028740NIA NIH HHS R01 AG059416NIA NIH HHS R01 AG089192NIA NIH HHS T32 AG062728
6 · The paper itself

Abstract

Circadian rhythms are inherent cycles of physiology and behavior that occur over approximately 24 h and are modulated by the cell-autonomous molecular clock. The molecular clocks throughout the body are aligned by the suprachiasmatic nucleus to contribute to robust daily variation of physiology, including core temperature, blood pressure, and heart rate. Alterations to the alignment of circadian clocks and changes to circadian rhythms of behavior and physiological processes are contributors to parameters that impact health and disease. In this review, we summarize what is known about changes to circadian rhythms of human behavior and physiology during older adulthood and the opportunities for future investigation of circadian physiology in older adults.

Identifiers

PMID42344441
PMCPMC13290292

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.