Evidence map›Paper›PMID 42344438›Full record

ArticleJournal of osteoporosis2026

Sex-Specific Biological Predictors for Identifying Individuals With Low Bone Mineral Density Using the Taiwan Biobank Database.

Yu-Hsu Chen, Yu-Pao Hsu, Ming-Te Cheng, Shau-Kwaun Chen, Jia-Wen Guo

Abstract read
In one paragraph

Article in Journal of osteoporosis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yu-Hsu ChenDepartment of Orthopedic Surgery, Ministry of Health and Welfare, Taoyuan General Hospital, Taoyuan, Taiwan, tygh.gov.tw.ORCID https://orcid.org/0000-0001-5535-9705
Yu-Pao HsuDepartment of Orthopedic Surgery, Ministry of Health and Welfare, Taoyuan General Hospital, Taoyuan, Taiwan, tygh.gov.tw.ORCID https://orcid.org/0000-0003-3797-4514
Ming-Te ChengDepartment of Orthopedic Surgery, Ministry of Health and Welfare, Taoyuan General Hospital, Taoyuan, Taiwan, tygh.gov.tw.ORCID https://orcid.org/0000-0002-1742-0488
Shau-Kwaun ChenInstitute of Neuroscience, National Chengchi University, Taipei, Taiwan, nccu.edu.tw.ORCID https://orcid.org/0000-0002-0701-6799
Jia-Wen GuoCollege of Nursing, University of Utah, Salt Lake City, Utah, USA, utah.edu.ORCID https://orcid.org/0000-0002-4698-4696

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteoporosis has seen a rapid rise in Taiwan due to its aging population. The pathogenesis of low bone mineral density (BMD) differs between women and men, highlighting the critical need to explore sex-specific biological predictor variables-an area with significant knowledge gaps. This study aimed to identify sex-specific predictors using a population database through machine learning. We conducted a retrospective cross-sectional study of 19,868 individuals aged 40 and above from the Taiwan Biobank database who had no cancer diagnosis and underwent BMD examinations between 2020 and 2022, with available demographic, laboratory, and physical examination data. The Extreme Gradient Boosting (XGBoost) model was employed to identify patterns of predictor variables for low BMD. SHapley Additive exPlanations (SHAP) were applied to visualize and interpret the contribution of each predictor to low BMD in women and men. Among participants, 63% (

Identifiers

PMID42344438
PMCPMC13288052

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.