ReviewHealth science reports2026
Association Between Dietary Total Fat Intake and Risk of Breast Cancer: A Meta-Analysis of Case-Control and Cohort Studies.
Review in Health science reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and Aims: Breast cancer represents the most prevalent malignant neoplasm and remains a principal cause of mortality among women worldwide. Despite extensive investigation, the association between dietary fat intake and breast cancer risk has yet to be definitively established. Consequently, this study aimed to conduct a systematic review and meta-analysis of existing case-control and cohort studies to elucidate the relationship between overall dietary fat consumption and breast cancer risk. Methods: A systematic search was conducted across online databases up to May 2025 to identify relevant case-control and cohort studies. The meta-analysis employed a random-effects model to pool multivariable-adjusted effect sizes (ESs), evaluating heterogeneity using the Results: The meta-analysis of 75 ESs from case-control studies indicated that women with the highest total dietary fat intake had a significantly increased risk of breast cancer compared to those with the lowest intake (ES: 1.23; 95% CI: [1.12, 1.34]; Conclusion: Case-control studies demonstrate a significant association between total dietary fat intake and breast cancer risk, whereas cohort studies do not report a statistically significant relationship. This disparity suggests a possible short-term effect of dietary fat on breast cancer risk, while evidence regarding its long-term impact remains inconclusive and warrants further investigation.
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