Evidence map›Paper›PMID 42344370›Full record

ArticleEndoscopy international open2026

Endoscopic ultrasound-directed transenteric ERCP in patients with benign and malignant diseases and inaccessible biliary system.

Leonie Grossmann, Thomas Veiser, Philipp Euler, Nicole Balasus, Tobias Dertmann, Maximilian Schneider, Torsten Beyna

Abstract read
In one paragraph

Article in Endoscopy international open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Leonie GrossmannDepartment of Internal Medicine and GastroenterologyEvangelisches Krankenhaus DüsseldorfDüsseldorfNRWGermany.ORCID 0009-0004-9427-7015
Thomas VeiserDepartment of Internal Medicine and GastroenterologyEvangelisches Krankenhaus DüsseldorfDüsseldorfNRWGermany.
Philipp EulerDepartment of Internal Medicine and GastroenterologyEvangelisches Krankenhaus DüsseldorfDüsseldorfNRWGermany.
Nicole BalasusDepartment of Internal Medicine and GastroenterologyEvangelisches Krankenhaus DüsseldorfDüsseldorfNRWGermany.
Tobias DertmannDepartment of Internal Medicine and GastroenterologyEvangelisches Krankenhaus DüsseldorfDüsseldorfNRWGermany.
Maximilian SchneiderDepartment of Internal Medicine and GastroenterologyEvangelisches Krankenhaus DüsseldorfDüsseldorfNRWGermany.
Torsten BeynaDepartment of Internal Medicine and GastroenterologyEvangelisches Krankenhaus DüsseldorfDüsseldorfNRWGermany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and study aims: Patients requiring biliary interventions with endoscopically inaccessible papilla or biliodigestive anastomosis represent a challenge in clinical practice. Historically, percutaneous transhepatic biliary drainage (PTBD) has often been the only viable treatment after failed endoscopic attempts. Recently, endoscopic ultrasound (EUS)-guided techniques have emerged as promising alternatives. This study evaluated the feasibility and safety of EUS-guided transenteric ERCP (EDEE) at a tertiary referral center. Patients and methods: This retrospective, single-center study included patients who underwent EDEE between February 2020 and November 2025. Primary endpoints were safety and overall technical success, defined as successful creation of an EUS-guided anastomosis (EA) using a lumen-apposing metal stent (LAMS) followed by endoscopic retrograce cholangiopancreatography (ERCP) via LAMS. Secondary endpoints included clinical success, need for reinterventions, and procedure characteristics. Results: A total of 24 patients (70.3 ± 12.6 years; 6 female) were analyzed. Sixteen patients had surgically altered anatomy (5 Whipple, 11 Roux-en-Y), and eight presented with malignant gastric outlet obstruction. EA and ERCP via LAMS were conducted in two stages with a median interval of 29.5 days. In 15 patients, the afferent loop was accessed after filling via a previously placed PTBD, which was removed after EDEE. Technical success was 100% (24/24) for EA and 87.5% (21/24) for ERCP via LAMS; overall technical and clinical success were 87.5% (21/24). Procedure-related complications occurred in two patients (8.3%), including one aspiration pneumonia and one LAMS misplacement. Conclusions: This study suggests that EDEE is a feasible and safe method for biliary drainage in patients with inaccessible biliary anatomy, demonstrating high technical and clinical success in both malignant and benign conditions being performed at a highly specialized tertiary center.

Indexed as

Endoscopic ultrasonographyERC topicsIntervention EUSPancreatobiliary (ERCP/PTCD)StonesStrictures

Identifiers

PMID42344370
PMCPMC13289966

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.