Evidence map›Paper›PMID 42344211›Full record

ArticleOrganic process research & development2026

Sulfoximine and Triazine-Acid Adduct Behavior in Aqueous HPMC: A Fast and Convenient

Dhanush Pradeep Chethikkattil, Ashish Dusunge, Michael Harmata, Wilfried M Braje, Sachin Handa

Abstract read
In one paragraph

Article in Organic process research & development, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dhanush Pradeep ChethikkattilDepartment of Chemistry, University of Missouri, 601 S College Ave, Columbia, Missouri 65211, United States.
Ashish DusungeDepartment of Chemistry, University of Missouri, 601 S College Ave, Columbia, Missouri 65211, United States.ORCID https://orcid.org/0009-0008-2509-760X
Michael HarmataDepartment of Chemistry, University of Missouri, 601 S College Ave, Columbia, Missouri 65211, United States.ORCID https://orcid.org/0000-0003-3894-2899
Wilfried M BrajeSmall Molecule Therapeutics & Platform Technologies, AbbVie Deutschland GmbH & Co. KG, Ludwigshafen 67061, Germany.
Sachin HandaDepartment of Chemistry, University of Missouri, 601 S College Ave, Columbia, Missouri 65211, United States.ORCID https://orcid.org/0000-0002-7635-5794

Funding

New Catalytic Technologies Impactful to Synthesis of PharmaceuticalsR35GM159617 · NIGMS · UNIVERSITY OF MISSOURI-COLUMBIA · PI Sachin Handa · 2025 to 2026
$801k
NIGMS NIH HHS R35 GM159617
6 · The paper itself

Abstract

Sulfoximines are valuable scaffolds in pharmaceuticals, yet their aqueous-phase stability and reactivity remain underexplored. We report a systematic study of sulfoximine-carboxylic acid coupling in water using hydroxypropyl methylcellulose (HPMC) as a microenvironment. In situ

Indexed as

chemistry in waterhydroxypropyl methylcelluloseN-arylationreaction intermediatessulfoximines

Identifiers

PMID42344211
PMCPMC13288916

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.