ArticleTH open : companion journal to thrombosis and haemostasis2026
Characterisation and Enhanced Residual Risk Stratification of Long-Term Post-Discharge Ischaemic Events After Atrial Fibrillation Catheter Ablation.
Article in TH open : companion journal to thrombosis and haemostasis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Although the incidence of thromboembolic events after catheter ablation for atrial fibrillation (AF) is low, the residual risk persists. The nature of these long-term events remains poorly characterized, and optimal risk stratification is challenging. We therefore aimed to characterize the postablation ischemic events and develop an enhanced risk stratification model. Methods: This single-center historical cohort study enrolled 1,163 patients who underwent initial AF ablation. The primary endpoint was a composite of postdischarge ischemic events (ischemic stroke, transient ischemic attack, and systemic arterial thromboembolism [SE]). The predictability of clinically available risk scores and individual parameters, including left atrial volume index (LAVI), was assessed. The new model combining the strongest predictors was benchmarked against the risk score alone. Results: Over a median follow-up of 5.1 (interquartile range: 3.1-7.1) years, 24 patients (2.1%) experienced an ischemic event (incidence: 0.38 per 100 person-years [95% confidence interval, 0.24-0.57]). AF-related etiologies (cardioembolic stroke/SE) accounted for 42% of events. More than half of the events (54%) occurred when the patients were in sinus rhythm. CHA Conclusion: In this long-term analysis, postablation ischemic events were infrequent and of mixed etiology, with noncardioembolic causes being common. A combined model integrating CHA
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