Evidence map›Paper›PMID 42343969›Full record

ArticleFEMS microbes2026

Acetate to caproate: metagenomic insights into functional shifts in a methane-arrested anaerobic bioreactor.

Laura G Schaerer, Ryan S Anderson, Joshua Chan, Susan K De Long

Abstract read
In one paragraph

Article in FEMS microbes, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Laura G SchaererDepartment of Civil and Environmental Engineering, Colorado State University, Fort Collins, CO 80523, United States.ORCID https://orcid.org/0000-0001-9820-3452
Ryan S AndersonDepartment of Civil and Environmental Engineering, Colorado State University, Fort Collins, CO 80523, United States.ORCID https://orcid.org/0000-0002-7572-1668
Joshua ChanSchool of Biomedical and Chemical Engineering, Colorado State University, Fort Collins, CO 80523, United States.
Susan K De LongDepartment of Civil and Environmental Engineering, Colorado State University, Fort Collins, CO 80523, United States.ORCID https://orcid.org/0000-0002-3160-2392

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Methane-arrested anaerobic digestion (AAD) is a waste management strategy that produces carboxylic acid precursors to industrial products (fuels, bio-based polymers, and pharmaceuticals) from organic wastes. A major challenge preventing application of AAD is highly variable product profiles resulting from an inability to control the microbial communities underlying waste decomposition and product biosynthesis. Over time, lactic acid bacteria (LAB) often dominate AAD bioreactors and overproduce shorter chain acids causing acidosis. Here an AAD bioreactor where caproic acid production increased from an average of 3.9 g/l to an average of 12.3 g/l when the feedstock was switched from manure and paperboard to food waste. Time series shotgun metagenomics is used to investigate how microbial dynamics drive performance shifts. The dominant LAB shifted from

Indexed as

bacteriocincaproic acidchain elongationcircular economylactic acid bacteriametagenomicsmethane-arrested anaerobic digestion

Identifiers

PMID42343969
PMCPMC13289733

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.