Evidence map›Paper›PMID 42343896›Full record

ReviewFrontiers in cell and developmental biology2026

Extracellular vesicles in bovine reproduction: their journey from gametogenesis to pregnancy.

Yulia N Cajas, Rosane Mazzarella, Meriem Hamdi, Gemma Millán de la Blanca, Juliano Coelho da Silveira, Claudia Lima Verde-Leal, Encina González, Dimitrios Rizos, Karina Cañón-Beltrán

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in cell and developmental biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yulia N CajasDepartment of Animal Reproduction, National Institute for Agriculture and Food Research and Technology (INIA-CSIC), Madrid, Spain.
Rosane MazzarellaDepartment of Animal Reproduction, National Institute for Agriculture and Food Research and Technology (INIA-CSIC), Madrid, Spain.
Meriem HamdiInstitute of Veterinary Anatomy, Vetsuisse Faculty Zurich, University of Zurich, Lindau, Switzerland.
Gemma Millán de la BlancaDepartment of Animal Reproduction, National Institute for Agriculture and Food Research and Technology (INIA-CSIC), Madrid, Spain.
Juliano Coelho da SilveiraDepartamento de Medicina Veterinária, Faculdade de Zootecnia e Engenharia de Alimentos, Universidade de São Paulo (FZEA-USP), Pirassununga, Brazil.
Claudia Lima Verde-LealDepartamento de Medicina Veterinária, Faculdade de Zootecnia e Engenharia de Alimentos, Universidade de São Paulo (FZEA-USP), Pirassununga, Brazil.
Encina GonzálezDepartment of Anatomy and Embryology, Veterinary Faculty, Complutense University of Madrid (UCM), Madrid, Spain.
Dimitrios RizosDepartment of Animal Reproduction, National Institute for Agriculture and Food Research and Technology (INIA-CSIC), Madrid, Spain.
Karina Cañón-BeltránDepartment of Animal Reproduction, National Institute for Agriculture and Food Research and Technology (INIA-CSIC), Madrid, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extracellular vesicles (EVs), including exosomes and microvesicles, play a pivotal role in bovine reproduction by mediating communication between gametes, the developing embryo, and the maternal reproductive tract. These vesicles act as carriers of bioactive molecules, such as microRNAs, mRNAs, lipids, and proteins that regulate processes from gametogenesis to early pregnancy. The embryo-maternal dialogue, mediated by EVs, shapes the oviductal and uterine microenvironments, ensuring proper fertilization, embryonic development, and implantation. However,

Indexed as

cattleembryo developmentembryo maternal-communicationextracellular vesiclesmiRNAsoviductuterus

Identifiers

PMID42343896
PMCPMC13286908

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.