Trial reportNan fang yi ke da xue xue bao = Journal of Southern Medical University2026
[Image-guided application of plant pigment patch and laser microdot ablation for surface marking in radiotherapy for breast cancer: a randomized controlled trial].
Trial report in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
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Authors and funding
7 authors.
Funding
Abstract
objectivesTo validate the non-inferiority of plant-based pigment patches as surface markers for postoperative radiotherapy localization in breast cancer, evaluate their accuracy, durability and safety, and identify the factors influencing pigment fading to determine the patients eligible for these patches.
methodsIn this randomized controlled trial, 80 patients receiving their first course of postoperative radiotherapy for breast cancer were randomly assigned in a 1:1 ratio to plant-based pigment patch group (trial group) or conventional laser microdot tattoo group (control group). The primary outcome was 3-dimensional setup error (non-inferiority margin: 0.7 mm). The secondary outcomes included uniaxial errors, re-marking frequency, skin adverse events, patient comfort, and healthcare satisfaction. Linear mixed-effects models and Cox regression were used for data analyses.
resultsThe baseline characteristics of the patients were balanced between the two groups. The trial group demonstrated non-inferiority to the control group in setup accuracy (3-dimensional error: 3.12±1.14 mm
conclusionsPlant-based pigment patches are non-inferior to conventional laser microdots and offer comparable positioning accuracy with superior comfort and safety.
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