Evidence map›Paper›PMID 42343739›Full record

ArticleActas espanolas de psiquiatria2026

Bridging Three Decades: Global Self-Harm Trends From 1990-2021 and Projections to 2040.

Hong Zhu, Xuhong Zhang, Tiantian Chen, Zhixin Lim, Saboor Saeed, Jianping Tong, Ye Shen

Abstract read
In one paragraph

Article in Actas espanolas de psiquiatria, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Hong ZhuDepartment of Ophthalmology, The First Affiliated Hospital of Zhejiang University, 310003 Hangzhou, Zhejiang, China.
Xuhong ZhangDepartment of Ophthalmology, The First Affiliated Hospital of Zhejiang University, 310003 Hangzhou, Zhejiang, China.
Tiantian ChenCixi Mingguang Eye Hospital, 315300 Ningbo, Zhejiang, China.
Zhixin LimSchool of Medicine, Zhejiang University, 310003 Hangzhou, Zhejiang, China.
Saboor SaeedSchool of Medicine, Zhejiang University, 310003 Hangzhou, Zhejiang, China.
Jianping TongDepartment of Ophthalmology, The First Affiliated Hospital of Zhejiang University, 310003 Hangzhou, Zhejiang, China.
Ye ShenDepartment of Ophthalmology, The First Affiliated Hospital of Zhejiang University, 310003 Hangzhou, Zhejiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSelf-harm, which includes both nonsuicidal self-injury and suicidal behaviors, poses a major global public health challenge. This study provides a comprehensive analysis of trends in self-harm worldwide, the socioeconomic disparities associated with it, and future projections, using data from the Global Burden of Disease, Injuries, and Risk Factors Study (GBD) 2021.

methodsSelf-harm data were extracted from GBD 2021, including incidence, prevalence, mortality, years of life lost (YLLs), years lived with disability (YLDs), and disability-adjusted life years(DALYs) for 204 countries and territories from 1990 to 2021. Age-standardized rates and estimated annual percentage change (EAPC) were calculated. Inequality was assessed using the Slope Index of Inequality (SII) and Concentration Index (CI). Autoregressive Integrated Moving Average (ARIMA) models were employed to generate projections of self-harm burden from 2022 to 2040.

resultsThe global burden of self-harm is projected to change substantially by 2040, with deaths estimated to increase to 829,853 (95% Uncertainty Interval (UI), 262,233-1,397,474) and prevalence projected to rise to 35,863,341 (95% UI, 8,079,108-63,647,574) cases (representing a 131.9% increase from the 2021 baseline of 15,467,153 cases). From 1990 to 2021, age-standardized rates of self-harm demonstrated decreasing trends globally and across sociodemographic index (SDI) levels, with the largest declines observed in high-middle SDI countries. Gender disparities were evident, with more pronounced decreases in females. Inequalities in DALYs due to self-harm decreased over time but remained higher among females in lower-SDI populations.

conclusionsDespite decreasing age-standardized rates, the global burden of self-harm is projected to increase substantially by 2040, with driven by increasing incidence and prevalence in incidence and prevalence. Inequities persist, particularly among females in lower-SDI populations. Implementation of targeted prevention and intervention strategies, strengthening of mental health systems, and addressing social determinants of health are imperative to reduce the growing burden of self-harm worldwide.

Indexed as

Global HealthSelf-Injurious BehaviorDisability-Adjusted Life YearsFemaleForecastingHumansIncidenceMalePrevalenceSocioeconomic Disparities in HealthTime Factors

Identifiers

PMID42343739
PMCPMC13294765

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