ArticlePilot and feasibility studies2026
Weight management in obese cancer patients during curative active treatment: protocol for the CANOBESE feasibility study.
Article in Pilot and feasibility studies, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07058207 (Weight Management in Obese Cancer Patients During Curative Active Treatment), which is not on this map. Not yet cited in PubMed.
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The trial behind it
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Weight Management in Obese Cancer Patients During Curative Active Treatment (CANOBESE Study): A Feasibility Study
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14 authors.
Funding
Abstract
backgroundObesity is highly prevalent among patients with cancer and is associated with increased risks of treatment-related complications, poorer oncological outcomes, and long-term morbidity. Despite this, current oncology nutrition guidelines primarily address malnutrition and provide limited direction for clinical management of patients with obesity. Intentional weight loss interventions during cancer treatment are uncommon, partly due to concerns about safety and feasibility. The CANOBESE study aims to address this evidence gap by evaluating the feasibility of implementing a structured, multimodal weight management programme for patients with obesity undergoing curative oncological treatment.
methodsThis single-arm feasibility trial will recruit 50 adult patients with a BMI ≥ 30 kg/m DISCUSSION: The CANOBESE study represents one of the first efforts to assess whether a comprehensive lifestyle intervention can be effectively delivered to patients with obesity during curative cancer treatment. This protocol incorporates patient and public involvement, a multidisciplinary team approach, and real-world implementation considerations. Findings will inform the scalability of the intervention, characterize implementation challenges across a pragmatic oncology population, and guide the design of a future randomized controlled trial. The study is not intended to provide subgroup-specific clinical recommendations, but to generate feasibility data that may help refine tailored approaches to intentional weight management in oncology settings.
trial registrationClinicalTrials.gov identifier: NCT07058207. Registered on 9 July 2025. https://clinicaltrials.gov/study/NCT07058207 .
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