ArticleJournal of animal science and biotechnology2026
Multi-omics analysis reveals Parabacteroides distasonis and Kineothrix alysoides as potential key bacterial species associated with anemia in sows.
Article in Journal of animal science and biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
backgroundSow anemia has been reported to be associated with reduced reproductive performance. Additionally, anemia may alter gut microbiota composition. However, the gut microbiota and metabolic signatures specifically linked to sow anemia status remain poorly understood.
resultsCompared with normal sows, anemic sows had lower hemoglobin levels at gestational days 30, 90, and 110 (P < 0.0001). The litter size (16.68 vs. 17.13), live litter size (14.34 vs. 15.13), healthy litter size (13.40 vs. 14.36), and litter weight (18.77 vs. 19.50) of anemic sows were lower than normal sows, but there was no significant difference. Iron transport-related genes showed that placental ferritin expression was significantly higher in normal sows than in anemic sows (P = 0.003). Serum antioxidant analysis showed that total antioxidant capacity was significantly lower in anemic sows than in normal sows at gestational days 90 (P = 0.026) and 110 (P = 0.017). Superoxide dismutase activity was significantly lower in anemic sows than in normal sows at gestational day 90 (P = 0.004) and showed a decreasing trend at gestational day 110 (P = 0.072). Fecal 16S rRNA analysis revealed distinct gut microbiota compositions between normal and anemic sows. Untargeted metabolomics showed distinct intergroup separation, with significant enrichment of the cytochrome P450 pathway at gestational days 30 and 110 (P < 0.05). Furthermore, multiple bacterial taxa showed significant positive correlations with hemoglobin levels, including Christensenella hongkongensis, Gimesia aquarii, Shigella dysenteriae, Massiliimalia massiliensis, Kineothrix alysoides, Mediterraneibacter gnavus, Parabacteroides distasonis, and Treponema sp. Marseille-Q3903 (P < 0.05).
conclusionThis study reveals the gut microbial and metabolic characteristics between normal and anemic sows. Two key bacterial species, P. distasonis and K. alysoides, were identified as associated with anemia status in sows.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.