Evidence map›Paper›PMID 42343134›Full record

ArticleNature2026

The mutational landscape of STING-induced immunity.

Bing Zhang, Pengbiao Xu, Yu Meng, Laure Gallay, François Lestelle, Hélène Morel, Marie-Louise Frémond, Bruno E Correia, Andrea Ablasser

Abstract read
In one paragraph

Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Precision tuning of STING signaling: a mutational blueprint.Signal transduction and targeted therapy · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Bing Zhang *Global Health Institute, Swiss Federal Institute of Technology Lausanne (EPFL), Lausanne, Switzerland.ORCID http://orcid.org/0000-0002-9334-3947
Pengbiao Xu *Global Health Institute, Swiss Federal Institute of Technology Lausanne (EPFL), Lausanne, Switzerland.ORCID http://orcid.org/0000-0003-0098-8875
Yu Meng *Global Health Institute, Swiss Federal Institute of Technology Lausanne (EPFL), Lausanne, Switzerland.ORCID http://orcid.org/0009-0006-3273-6655
Laure GallayDepartment of Clinical Immunology, Edouard Herriot Hospital, Hospices Civils de Lyon, Lyon, France.ORCID http://orcid.org/0000-0002-7020-1954
François LestelleHospices Civils de Lyon, Centre de Référence Coordinateur Des Maladies Pulmonaires Rares (OrphaLung), Hôpital Louis Pradel, Service de Pneumologie, Lyon, France.
Hélène MorelDepartment of Genetics, Bichat Claude-Bernard Hospital, Assistance Publique - Hôpitaux de Paris (AP-HP), Paris, France.
Marie-Louise FrémondUniversité Paris Cité, Imagine Institute, Laboratory of Neurogenetics and Neuroinflammation, INSERM UMR 1163, Paris, France.
Bruno E CorreiaLaboratory of Protein Design and Immunoengineering, Swiss Federal Institute of Technology Lausanne (EPFL), Lausanne, Switzerland.ORCID http://orcid.org/0000-0002-7377-8636
Andrea AblasserGlobal Health Institute, Swiss Federal Institute of Technology Lausanne (EPFL), Lausanne, Switzerland. andrea.ablasser@epfl.ch.ORCID http://orcid.org/0000-0002-8475-8999

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stimulator of interferon genes (STING) is an evolutionary conserved immune signalling protein with key roles in host defence, cancer, senescence and inflammation

Indexed as

Nucleotides, CyclicRegulatory Sequences, Nucleic AcidSTING ProteinAnimalsAutophagycGAS-STING Signaling PathwayCryoelectron MicroscopyHumansInterferon Type ILigandsMembrane ProteinsModels, MolecularMutationSignal Transductioncyclic guanosine monophosphate-adenosine monophosphateInterferon Type ILigandsMembrane ProteinsNucleotides, CyclicSTING1 protein, humanSTING Protein

Identifiers

PMID42343134
PMCPMC13421317

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.