ReviewJournal of general internal medicine2026
Statin-Related Myotoxicity: A Narrative Review and Practical Approach for General Internists.
Review in Journal of general internal medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Statins constitute a common class of therapeutic agents indicated for the treatment of hyperlipidaemia, cerebrovascular, and cardiovascular disease. Statins are widely used due to their well-established cardiovascular benefits, pleiotropic effects (e.g. atherosclerotic plaque-stabilising effects), and favourable safety profile. Yet, with its widespread usage, clinicians should be aware of its common side effect in the form of statin-associated muscular symptoms that potentially develop in 5-10% of patients. While most of these adverse effects are benign and amenable to dose reduction or switching to an alternative statin, rare cases occur where patients develop severe myopathies, rhabdomyolysis, and even a potentially dangerous form of autoimmune necrotising myositis. In this narrative review article, we sought to provide a practical and up-to-date overview and approach to statin-associated myotoxicity for general internists who would manage these patients in their practice.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.