ArticleJournal of neurology2026
Preoperative imaging evaluation of primary trigeminal neuralgia using 3D TOF-MRA and 3D FIESTA-c: A retrospective study of 412 cases.
Article in Journal of neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate the clinical value of three-dimensional time-of-flight magnetic resonance angiography (3D TOF-MRA), three-dimensional fast imaging employing steady-state acquisition with phase cycling (3D FIESTA-c), and their combination for preoperative assessment of responsible vessels in primary trigeminal neuralgia (PTN) before microvascular decompression (MVD).
methodsWe retrospectively reviewed 412 patients with PTN confirmed by MVD who underwent preoperative 3D TOF-MRA and 3D FIESTA-c. Intraoperative findings served as the reference standard. Diagnostic performance was assessed using 2 criteria: binary identification of the presence or absence of a responsible vessel and complete concordance of vessel type. Agreement with surgical findings was evaluated using Cohen's kappa. Subgroup analyses were performed according to responsible vessel type.
resultsResponsible vessels were identified intraoperatively in 407 of 412 patients (98.79%), whereas no responsible vessel was found in 5 patients (1.21%). The superior cerebellar artery (SCA) was the most common responsible vessel (250/412, 60.68%), followed by involvement of the SCA and petrosal vein (54/412, 13.11%). Under binary criteria, the accuracy of 3D TOF-MRA, 3D FIESTA-c, and the combined approach was 90.53%, 91.99%, and 96.36%, respectively, with a significant overall difference (Cochran's Q = 23.400, P < 0.001). Under complete concordance criteria, the corresponding matching rates were 74.27%, 82.77%, and 87.86%, respectively, with kappa values of 0.531, 0.702, and 0.786 (Cochran's Q = 64.892, P < 0.001). Pairwise comparisons showed that the combined approach outperformed either sequence alone, and 3D FIESTA-c also outperformed 3D TOF-MRA under complete concordance. The combined approach also performed better in the SCA and anterior inferior cerebellar artery (AICA) subgroups.
conclusionThe combination of 3D TOF-MRA and 3D FIESTA-c improves preoperative assessment of responsible vessels in PTN, with higher diagnostic accuracy and better agreement with intraoperative findings than either modality alone.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.