ReviewNature chemical biology2026
Image-guided activation of drugs with electromagnetic radiation.
Review in Nature chemical biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Image-guided pharmacotherapy, in which drug activity is strictly confined to disease areas revealed by medical imaging modalities, holds great promise for the development of personalized medicine. A key step in realizing this potential is the development of safe and precise methods for drug activation. Electromagnetic radiation, spanning the energy ranges from γ-rays to ultraviolet-visible and infrared light, has emerged as a method of choice for this purpose. Because many imaging modalities rely on electromagnetic radiation to generate signals (for example, optical and optoacoustic imaging, computed tomography and positron emission tomography), this phenomenon can be used to both activate a drug and monitor tissue response, creating a theranostic synergy. This Perspective outlines the molecular basis for drug activation with electromagnetic radiation, offers a clinical perspective in discussing the most suitable applications and advantages available and discusses the challenges, such as the delivery of light at the site of interest, and steps needed for successful translation into daily clinical practice.
Indexed as
Identifiers
42342845What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.