Evidence map›Paper›PMID 42341318›Full record

ArticleJMIR formative research2026

Supporting Student Mental Health With the Safespace Generative AI Chatbot: Mixed Methods Feasibility Study.

Matteo Pinna, Sergio Galletta, Elliott Ash, Timon Elmer

Abstract read
In one paragraph

Article in JMIR formative research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Matteo PinnaCenter for Law and Economics, Department of Humanities, Social and Political Sciences, ETH Zürich, Haldeneggsteig 4, Zürich, 8092, Switzerland, +41 44 6324586.ORCID 0000-0002-4784-7255
Sergio GallettaCenter for Law and Economics, Department of Humanities, Social and Political Sciences, ETH Zürich, Haldeneggsteig 4, Zürich, 8092, Switzerland, +41 44 6324586.ORCID 0000-0002-2254-9147
Elliott AshCenter for Law and Economics, Department of Humanities, Social and Political Sciences, ETH Zürich, Haldeneggsteig 4, Zürich, 8092, Switzerland, +41 44 6324586.ORCID 0000-0002-6817-7529
Timon ElmerApplied Social and Health Psychology, Department of Psychology, University of Zürich, Zürich, Switzerland.ORCID 0000-0003-4354-4457

Funding

Swiss National Science Foundation POC 231016Swiss National Science Foundation PZ00P1_208742
6 · The paper itself

Abstract

Background: Generative artificial intelligence (GenAI) chatbots have the potential to provide personalized mental health support to individuals at scale. Objective: This study evaluates the feasibility and usage patterns of the Safespace GenAI chatbot, an artificial intelligence (AI)-driven smartphone app that offers a large language model-powered interactive chatbot to support mental health. Methods: Using a mixed methods approach, we explored baseline attitudes toward GenAI chatbots and chatbot usage patterns, conducted a qualitative content analysis of participants' experiences, and descriptively assessed patterns related to preintervention depressive symptoms. The study included an initial sample of 42 university students, 20 of whom actively used the chatbot over 2 to 4 weeks, generating 286 user-chatbot interactions. Results: Preintervention surveys indicated that the majority of participants anticipated that the chatbot would be helpful (27/42, 64%) and that they trusted its privacy safeguards (39/42, 93%). Usage patterns suggested that the highest levels of interaction occurred early in the morning and late at night, when peer and professional support may be inaccessible. The qualitative analysis indicated that participants appreciated using the chatbot for reflection as a blended-care tool between their counseling sessions, while also naming technical barriers and specific design needs required to sustain engagement. In addition, our exploratory analyses descriptively showed that participants with elevated depression scores engaged in emotional disclosure during 99% (38 sessions with 8 participants) of their sessions, compared to 84% (26 sessions of 12 participants) of those with low symptoms. Due to the small sample size, future adequately powered studies are needed to inferentially examine these observed patterns. Conclusions: These findings provide initial insights into the usage and engagement dynamics of the Safespace GenAI chatbot and highlight directions for future research to optimize GenAI-driven mental health interventions.

Indexed as

Mental HealthStudentsAdultFeasibility StudiesFemaleGenerative Artificial IntelligenceHumansLarge Language ModelsMaleQualitative ResearchSurveys and QuestionnairesUniversitiesYoung AdultchatbotdepressionfeasibilityGenAIgenerative artificial intelligencelarge language modelmental healthmixed methodsqualitative content analysisstudents

Identifiers

PMID42341318
PMCPMC13293566

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.