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ArticleEuropean journal of orthopaedic surgery & traumatology : orthopedie traumatologie2026

Management of stiffness after total knee arthroplasty: influence of intervention timing and surgical technique on clinical outcomes.

Guillermo Peretó Villaescusa, Alexandre Coelho, Giovanni Grillo, Sergi Gil-González, J M Peñalver-Matamoros, David Martí-Garín, Xavier Pelfort-López

Abstract readComparative Study
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In one paragraph

Article in European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Guillermo Peretó VillaescusaDepartment of Orthopedics and Traumatology, Knee Unit, Parc Taulí Hospital Universitari, Institut d'Investigació I Innovació Parc Taulí (I3PT-CERCA) Universitat Autònoma Barcelona (UAB), Sabadell, Spain. gpereto@tauli.cat.
Alexandre CoelhoDepartment of Orthopedics and Traumatology, Knee Unit, Parc Taulí Hospital Universitari, Institut d'Investigació I Innovació Parc Taulí (I3PT-CERCA) Universitat Autònoma Barcelona (UAB), Sabadell, Spain. acoelho@tauli.cat.
Giovanni GrilloDepartment of Orthopedics and Traumatology, Knee Unit, Parc Taulí Hospital Universitari, Institut d'Investigació I Innovació Parc Taulí (I3PT-CERCA) Universitat Autònoma Barcelona (UAB), Sabadell, Spain.
Sergi Gil-GonzálezDepartment of Orthopedics and Traumatology, Knee Unit, Parc Taulí Hospital Universitari, Institut d'Investigació I Innovació Parc Taulí (I3PT-CERCA) Universitat Autònoma Barcelona (UAB), Sabadell, Spain.
J M Peñalver-MatamorosDepartment of Orthopedics and Traumatology, Knee Unit, Parc Taulí Hospital Universitari, Institut d'Investigació I Innovació Parc Taulí (I3PT-CERCA) Universitat Autònoma Barcelona (UAB), Sabadell, Spain.
David Martí-GarínDepartment of Orthopedics and Traumatology, Knee Unit, Parc Taulí Hospital Universitari, Institut d'Investigació I Innovació Parc Taulí (I3PT-CERCA) Universitat Autònoma Barcelona (UAB), Sabadell, Spain.
Xavier Pelfort-LópezDepartment of Orthopedics and Traumatology, Knee Unit, Parc Taulí Hospital Universitari, Institut d'Investigació I Innovació Parc Taulí (I3PT-CERCA) Universitat Autònoma Barcelona (UAB), Sabadell, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPostoperative knee stiffness following total knee arthroplasty (TKA) is a challenging complication that may require surgical intervention when conservative treatment fails. Although manipulation under anesthesia (MUA) and arthroscopic arthrolysis (AA) are commonly used treatments, their comparative effectiveness and the role of timing in clinical outcomes remain uncertain. PURPOSE: To compare clinical outcomes of MUA and AA for postoperative knee stiffness after TKA and to evaluate the impact of timing from index arthroplasty on range of motion (ROM) improvement.

methodsA retrospective cohort study was conducted including patients treated for postoperative knee stiffness following TKA between 2003 and 2023, with a minimum 12-month follow-up. Patients underwent MUA or AA. ROM was assessed preoperatively, intraoperatively, and at final follow-up. Outcomes were analysed according to surgical technique and timing of intervention. Complications were recorded.

resultsEighty-four patients were included (mean age 67.8 ± 7.5 years; 63.5% women), with 52 undergoing MUA and 32 AA. Preoperative ROM was comparable between groups (66.1° ± 14.2° vs 61.3° ± 12.3°; p = 0.353). Both techniques significantly improved ROM at final follow-up, with no between-group differences (90.9° ± 11.3° vs 86.7° ± 11.3°; p = 0.361). Mean ROM gain was similar (24.8° ± 12.8° vs 25.4° ± 11.9º; mean difference 0.6, p = 0.732). Earlier intervention was associated with greater ROM gain, with higher improvements observed within 0-3 and 3-6 months compared to > 6 months (28.1° ± 14.2°, 30.1° ± 13.1°, and 21.3° ± 25.9°, respectively; p = 0.038). Subgroup analysis by timing interval showed no differences between MUA and AA.

conclusionBoth MUA and AA were effective and demonstrated no significant difference in ROM improvement following TKA stiffness. Earlier intervention was associated with greater ROM gains, suggesting that timing may be an important factor in optimizing outcomes.

Indexed as

Arthroplasty, Replacement, KneeArthroscopyKnee JointManipulation, OrthopedicPostoperative ComplicationsAgedFemaleHumansMaleMiddle AgedRange of Motion, ArticularRetrospective StudiesTime FactorsTreatment OutcomeArthrofibrosisArthroscopic arthrolysisMobilization under anesthesiaROMStiffnessTKA

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.