ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2026
Tablet-based multi-stimulus perimetry for glaucoma screening.
Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeTo evaluate the Multi-Stimulus Vision Tester for a single eye (MVT-s), a tablet-based perimetry tool for detecting glaucomatous visual field (VF) defects.
participantsForty-two eyes of 42 patients with glaucoma were classified into three stages on the basis of the mean deviation (MD) measured by the imo perimeter: early (12 eyes), moderate (19 eyes), and advanced (11 eyes), with an overall median MD of MD of - 8.5 dB (IQR, - 13.2 to - 5.2). Additionally, 39 eyes of 39 visually normal individuals were included as controls.
methodsAll participants underwent testing with the MVT-s and standard automated perimetry using the imo perimeter. The MVT-s used a multipoint stimulation paradigm with flickering stimuli, presenting up to three test points simultaneously. Participants recorded their responses by directly touching the stimulus locations on the screen. The MVT-s test was performed three times on the same day for each participant. We evaluated the relationship between the number of abnormal points detected by the MVT-s and MD obtained with the imo, diagnostic accuracy using sensitivity, specificity, and receiver operating characteristic curve analysis, short-term test-retest reproducibility using the intraclass correlation coefficient (ICC), and examination time.
resultsAbnormal points increased with disease severity (median 7.5, 17.0, and 22.0 in early, moderate, and advanced glaucoma; p < 0.001) and correlated with MD (ρ = - 0.84). Discrimination was high (AUC 0.93). Using cutoffs of ≥ 3/ ≥ 4/ ≥ 5 abnormal points, sensitivities were 92.9/92.9/90.5% and specificities were 79.5/82.1/84.6%. Test-retest reproducibility was good, with ICCs of 0.95 overall, 0.82 in normal eyes, and 0.93 in glaucomatous eyes.
conclusionThe MVT-s demonstrated high diagnostic accuracy and reproducibility for detecting glaucomatous VF defects, with a relatively short examination time, suggesting its potential as a practical screening and complementary assessment tool in glaucoma care.
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