Evidence map›Paper›PMID 42340376›Full record

ReviewInnere Medizin (Heidelberg, Germany)2026

[Optimal blood pressure control in patients with diabetes and arterial hypertension: interpreting the BPROAD study].

Jan Galle, Julia Weinmann-Menke

Abstract readEnglish AbstractReview
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In one paragraph

Review in Innere Medizin (Heidelberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jan GalleKlinik für Nephrologie und Dialyseverfahren, Klinikum Lüdenscheid, Paulmannshöher Straße 14, 58515, Lüdenscheid, Deutschland. jan.galle@t-online.de.
Julia Weinmann-MenkeKlinik für Nephrologie des Zentrums für Innere Medizin, Universitätsklinikum Heidelberg, Heidelberg, Deutschland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

National and international guidelines for the treatment of arterial hypertension have changed significantly over the last decades. Until 2009, most hypertension guidelines suggested: "the lower the better". This point of view had been revised in the second decade of this century, mainly due to the lack of data supporting low target values. However, the next turnaround was prompted by interpretation of the data from the Systolic Blood Pressure Intervention Trial (SPRINT) in 2015, which provided evidence for a lower rate of cardiovascular events when systolic blood pressure was lowered below 120 mm Hg. Since the SPRINT trial had excluded patients with diabetes, the Blood Pressure Control Target in Diabetes (BPROAD) trial (2025), which included diabetics, received major attention. The BPROAD trial came to similar conclusions as the SPRINT trial, now supporting the benefit of lowering systolic blood pressure below 120 mm Hg for a broader range of patients. However, the method of measuring blood pressure, as well as the individual tolerability of low blood pressure targets, must also be taken into consideration.

Indexed as

Antihypertensive AgentsDiabetes Mellitus, Type 2HypertensionBlood PressureBlood Pressure DeterminationBlood Pressure Monitoring, AmbulatoryHumansPractice Guidelines as TopicRandomized Controlled Trials as TopicAntihypertensive AgentsBlood pressure reductionBlood pressure targetsCardiovascular riskHome blood pressure measurementStandardized blood pressure measurement

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.