Evidence map›Paper›PMID 42340225›Full record

ArticleLa Medicina del lavoro2026

The Evolving Landscape of Contact Dermatitis Diagnosis: A Critical Appraisal of Recent Regulatory Constraints.

Marco Polonioli, Marco Dubini, Silvia Mariel Ferrucci, Paolo Marraccini

Abstract read
In one paragraph

Article in La Medicina del lavoro, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Marco PolonioliPost Graduation School of Occupational Medicine, Università degli Studi di Milano, Milan, Italy.
Marco DubiniGeneral Medicine, Immunology, and Allergology Unit, IRCCS Foundation Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy.
Silvia Mariel FerrucciDermatology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Paolo MarracciniGeneral Medicine, Immunology, and Allergology Unit, IRCCS Foundation Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The current limited availability of patch tests for diagnosing Allergic contact dermatitis (ACD) and occupational or non-professional diseases, in accordance with AIFA regulations, has significantly affected the diagnostic approach for patients and affected workers. The issue is even more severe for haptens of occupational origin. In occupational medicine, the patch test is crucial for establishing the causal link between the skin disease and the patient's work activities. Accurate diagnosis is essential for occupational physicians both to determine the need for a job change and to assess workers' compensation. Due to limited diagnostics and regulatory restrictions, it remains impossible to diagnose occupational ACD. In this context, occupational doctors will focus on primary prevention by avoiding risk products and replacing them with non-sensitizing or non-cross-reactive alternatives. This paper addresses the challenges posed by the new AIFA (Italian Medicines Agency) diagnostic restrictions and explores potential solutions and future perspectives.

Indexed as

Dermatitis, Allergic ContactHaptensOccupational DiseasesOccupational MedicinePatch TestsAllergy and ImmunologyHumansItalyHaptens

Identifiers

PMID42340225
PMCPMC13353169

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.