Evidence map›Paper›PMID 42340107›Full record

ArticleJournal of pregnancy2026

Selective Reduction of Multiple Pregnancies Into Singleton Pregnancy: Treatment Analysis for Fetal Position.

Haiyan Liu, Run Chen, Xuan Huang, Yi Zhou, Yanmin Luo, Zhuyu Li

Abstract read
In one paragraph

Article in Journal of pregnancy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Haiyan LiuDepartment of Obstetrics and Gynecology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China, sysu.edu.cn.ORCID https://orcid.org/0009-0007-1041-8688
Run ChenDepartment of Obstetrics and Gynecology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China, sysu.edu.cn.ORCID https://orcid.org/0000-0001-6990-7995
Xuan HuangDepartment of Obstetrics and Gynecology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China, sysu.edu.cn.
Yi ZhouDepartment of Obstetrics and Gynecology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China, sysu.edu.cn.
Yanmin LuoDepartment of Obstetrics and Gynecology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China, sysu.edu.cn.ORCID https://orcid.org/0000-0002-7354-0767
Zhuyu LiDepartment of Obstetrics and Gynecology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China, sysu.edu.cn.ORCID https://orcid.org/0000-0002-2022-2220

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe rise in assisted reproductive technology has increased the prevalence of high-risk triplet pregnancies. Dichorionic triamniotic (DCTA) triplets-where a monochorionic-diamniotic (MCDA) twin pair shares a placenta-carry significant risks, including twin-to-twin transfusion syndrome. Although reducing a multifetal pregnancy to a singleton via MFPR leads to better outcomes, how the location of the reduced fetus within the uterus affects the success of the pregnancy is not addressed in current clinical guidance.

objectivesThis study compares obstetric outcomes based on the location of the reduced MCDA twin pair (superior vs. inferior position) in DCTA triplet pregnancies.

methodsA retrospective analysis was conducted on 200 patients who underwent MFPR to a singleton between 2013 and 2024. Patients were divided into Group A (MCDA pair located farther from the cervix/superior) and Group B (MCDA pair located closer to the cervix/inferior). Primary outcomes included miscarriage rates (before 24 weeks) and gestational age at delivery.

resultsGroup A demonstrated a significantly lower miscarriage rate (4.1% vs. 17.9%, p = 0.001) and a higher mean gestational age at delivery (38.38 vs. 37.36 weeks, p = 0.015) compared to Group B. Additionally, the incidence of low birth weight was significantly lower in Group A (10.3% vs. 26.6%, p = 0.004). No significant differences were found in perinatal death or Apgar scores between the groups.

conclusionsIn DCTA pregnancies, reducing the MCDA twin located farther from the cervix is associated with lower miscarriage rates and improved gestational outcomes.

Indexed as

Pregnancy Reduction, MultifetalPregnancy, TripletAbortion, SpontaneousAdultFemaleGestational AgeHumansPregnancyPregnancy OutcomeRetrospective Studiesdichorionic triamniotic pregnancyfetal reductionmiscarriagemonochorionic diamniotic trichorionic triamniotic pregnancypreterm birthtriplet pregnancies

Identifiers

PMID42340107
PMCPMC13292021

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.