Evidence map›Paper›PMID 42340043›Full record

ReviewRevista da Sociedade Brasileira de Medicina Tropical2026

Climate change and tropical medicine in the Amazon: contributions from a research center, gaps and future priorities.

Fernando Almeida-Val, Eduardo Fernandes Silva-Junior, Alexandre Vilhena Silva-Neto, Bernardo Maia Silva, Felipe Nery Saldanha Braga, Erika de Oliveira Gomes, Daniel Barros de Castro, Camila Fabbri, Luarle de Souza Lima, Felipe Leão Gomes Murta and 5 more

Abstract readReview
In one paragraph

Review in Revista da Sociedade Brasileira de Medicina Tropical, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. The sustained "re-enchantment" of research in tropical medicine in the Brazilian Amazon.Revista da Sociedade Brasileira de Medicina Tropical · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Fernando Almeida-ValFundação de Medicina Tropical Doutor Heitor Vieira Dourado, Manaus, AM, Brasil.ORCID http://orcid.org/0000-0001-9995-0249
Eduardo Fernandes Silva-JuniorUniversidade do Estado do Amazonas, Manaus, AM, Brasil.ORCID http://orcid.org/0000-0002-8420-6414
Alexandre Vilhena Silva-NetoUniversidade do Estado do Amazonas, Manaus, AM, Brasil.ORCID http://orcid.org/0000-0002-4375-3868
Bernardo Maia SilvaUniversidade do Estado do Amazonas, Manaus, AM, Brasil.ORCID http://orcid.org/0000-0002-5989-1288
Felipe Nery Saldanha BragaUniversidade do Estado do Amazonas, Manaus, AM, Brasil.ORCID http://orcid.org/0000-0002-4237-8744
Erika de Oliveira GomesFundação de Medicina Tropical Doutor Heitor Vieira Dourado, Manaus, AM, Brasil.ORCID http://orcid.org/0009-0008-4572-9117
Daniel Barros de CastroInstituto Nacional de Pesquisas na Amazônia, Manaus, AM, Brasil.ORCID http://orcid.org/0000-0001-5969-544X
Camila FabbriFundação de Medicina Tropical Doutor Heitor Vieira Dourado, Manaus, AM, Brasil.ORCID http://orcid.org/0009-0005-6017-6950
Luarle de Souza LimaFundação de Medicina Tropical Doutor Heitor Vieira Dourado, Manaus, AM, Brasil.ORCID http://orcid.org/0009-0007-6593-7274
Felipe Leão Gomes MurtaFundação de Medicina Tropical Doutor Heitor Vieira Dourado, Manaus, AM, Brasil.ORCID http://orcid.org/0000-0003-4414-3989
Rubelmar Maia de Azevedo Cruz-NetoUniversidade do Estado do Amazonas, Manaus, AM, Brasil.ORCID http://orcid.org/0000-0002-1408-5290
Taynna Vernalha Rocha AlmeidaUniversidade Federal do Amazonas, Manaus, AM, Brasil.ORCID http://orcid.org/0000-0001-9872-2420
Vanderson de Souza SampaioInstituto Todos pela Saúde, São Paulo, SP, Brasil.ORCID http://orcid.org/0000-0001-7307-8851
Guilherme Peixoto Tinôco ArêasUniversidade Federal do Amazonas, Manaus, AM, Brasil.ORCID http://orcid.org/0000-0002-7083-8314
Wuelton Marcelo MonteiroFundação de Medicina Tropical Doutor Heitor Vieira Dourado, Manaus, AM, Brasil.ORCID http://orcid.org/0000-0002-0848-1940

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Amazon Basin is undergoing rapid climatic and environmental changes, with direct impacts on infectious disease transmission and public health. Rising temperatures, altered rainfall patterns, and more frequent extreme events are reshaping vector and pathogen dynamics. Additionally, deforestation and land-use change increase human and animal exposure. These combined factors intensify the risk of disease transmission in the region. This narrative review synthesizes evidence generated by researchers from a reference center in tropical medicine in the Amazon, integrating epidemiological analyses, experimental studies, ecological and predictive modelling, and health systems research conducted over the past decade. The evidence indicates that temperature and hydrological variability affect vector competence, pathogen development, and host-vector contact rates, producing nonlinear and context-dependent transmission outcomes. Extreme hydroclimatic events additionally disrupt healthcare delivery, hinder surveillance, and compromise continuity of care for infections requiring sustained treatment, such as tuberculosis and HIV. Emerging advances, including species distribution modelling, remote sensing, and integrated climate-epidemiological surveillance, provide predictive capacity to anticipate outbreaks and identify emerging hotspots. However, substantial research gaps persist, particularly regarding multi-stressor interactions, mechanistic pathways of climate-pathogen-vector adaptation, and health system resilience under climatic extremes. From the perspective of a reference center that integrates education, research, and healthcare delivery in tropical medicine, this article articulates a research agenda for climate-informed tropical medicine, highlighting priorities for interdisciplinary research, surveillance innovation, and adaptive public health strategies in the Amazon and other climate-sensitive regions.

Indexed as

Climate ChangeTropical MedicineAnimalsBrazilEvidence GapsHumansTropical Climate

Identifiers

PMID42340043
PMCPMC13286602

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.