ArticleArquivos brasileiros de cardiologia2026
Impact of Population Aging on Cardiovascular Disease Prevalence in the Macroregions of Brazil: Forecasts to 2050.
Article in Arquivos brasileiros de cardiologia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
Cardiovascular diseases (CVD) have consistently been the leading cause of morbidity and mortality worldwide, with an increasing burden driven by demographic aging. Although Brazil mirrors this global pattern, this burden may be unevenly distributed across its macroregions. The main objective of this work is to investigate the trends in CVD prevalence in the macroregions of Brazil from 1990 to 2021 and to forecast scenarios to 2050, considering demographic aging. Crude and age-standardized prevalence rates were obtained from the Global Burden of Disease study. Neural state-space models were used to forecast trends to 2050, with 95% confidence intervals estimated via a Monte Carlo-like approach. Crude prevalence rates tend to rise substantially across all macroregions until 2050, with the central-west expected to see the highest rise (64.6% [52.3-79.5]) and the northeast the lowest (39.2% [33.4-46.5]). In contrast, age-standardized rates are expected to remain largely constant across the years, with only a modest increase observed in the northeast (<7%). Even under relatively constant age-standardized rates, health systems are expected to face growing clinical and economic challenges associated with an older and more multimorbid population. Regional disparities underscore the need for tailored prevention strategies to mitigate the burden of CVD in Brazil.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.