Evidence map›Paper›PMID 42339911›Full record

ArticleRevista da Associacao Medica Brasileira (1992)2026

Evaluation of the use of dienogest in women with deep endometriosis and ovarian endometrioma: a retrospective cohort study.

Arissa Onishi, Joao Paulo Leonardo-Pinto, Cristina Laguna Benetti-Pinto, Daniela Angerame Yela

Abstract read
In one paragraph

Article in Revista da Associacao Medica Brasileira (1992), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Arissa OnishiUniversidade Estadual de Campinas, School of Medical Sciences, Department of Gynecology and Obstetrics - Campinas (SP), Brazil.ORCID http://orcid.org/0009-0006-3900-1600
Joao Paulo Leonardo-PintoUniversidade Estadual de Campinas, School of Medical Sciences, Department of Gynecology and Obstetrics - Campinas (SP), Brazil.ORCID http://orcid.org/0000-0002-9698-8230
Cristina Laguna Benetti-PintoUniversidade Estadual de Campinas, School of Medical Sciences, Department of Gynecology and Obstetrics - Campinas (SP), Brazil.ORCID http://orcid.org/0000-0001-6198-5593
Daniela Angerame YelaUniversidade Estadual de Campinas, School of Medical Sciences, Department of Gynecology and Obstetrics - Campinas (SP), Brazil.ORCID http://orcid.org/0000-0003-3889-4778

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of this study was to evaluate the use of dienogest in the treatment of deep endometriosis and ovarian endometrioma.

methodsThis retrospective cohort study included 59 women diagnosed with ovarian endometrioma at a tertiary hospital between 2013 and 2018. Pain scores and endometrioma size were evaluated after 12 months of dienogest use, along with the women's sociodemographic characteristics.

resultsThe mean age of the participants was 35.7±6.9 years. Unilateral endometrioma was observed in 38.9% of cases. There was a significant reduction in dysmenorrhea (p=0.011) with dienogest use, but no reduction in other pain symptoms. A reduction in left ovarian volume (p=0.009), mean left endometrioma size (p=0.01), and lesion size in the anterior cul-de-sac (p=0.047) was observed after dienogest treatment. A positive correlation was found between dyschezia and lesions in the posterior cul-de-sac before initiation of dienogest treatment.

conclusionDienogest appears to reduce pain in women with deep endometriosis. Our findings support dienogest as an effective therapeutic option.

Indexed as

EndometriosisHormone AntagonistsNandroloneOvarian DiseasesAdultDysmenorrheaFemaleHumansPain MeasurementPelvic PainRetrospective StudiesTreatment OutcomedienogestHormone AntagonistsNandrolone

Identifiers

PMID42339911
PMCPMC13286519

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.