Observational studyAnnals of medicine2026
Paracervical block in office hysteroscopy with vaginoscopic approach to reduce patients' pain perception: a propensity score matching analysis.
Observational study in Annals of medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Clinical Factors Associated with Pain During Outpatient Hysteroscopy in a Standardized Vaginoscopic Setting: A Prospective Observational Study.Journal of clinical medicine · 2026Article
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPain perception is a major limitation of office hysteroscopy and may lead to premature suspension of the procedure. Current guidelines do not routinely recommend local analgesia, and the effectiveness of paracervical block during office hysteroscopy performed with a vaginoscopic approach remains insufficiently investigated.
objectivesThe primary objective was to assess whether paracervical block is associated with reduced pain perception during office hysteroscopy with a vaginoscopic approach. The secondary objective was to evaluate its impact on procedure suspension. MATERIALS AND
methodshis retrospective observational cohort study included patients undergoing diagnostic and/or operative office hysteroscopy between January 2018 and January 2022. Paracervical block was administered without speculum or tenaculum. Confounders were addressed using multivariable regression and propensity score matching.
resultsA total of 2,028 patients were analyzed. In patients who did not receive PB, nulliparity was associated with severe pain (aOR 2.87, 95% CI 1.20-6.85) and procedure suspension (aOR 3.07, 95% CI 1.27-7.39), and cervical canal stenosis with markedly increased odds of both severe pain (aOR 23.17, 95% CI 10.44-51.40) and suspension (aOR 25.10, 95% CI 11.19-56.30). In patients receiving PB, nulliparity was no longer significantly associated with either outcome, and the effect of cervical canal stenosis was substantially attenuated (aOR 2.68, 95% CI 1.57-4.58 for severe pain; aOR 3.70, 95% CI 2.07-6.62 for suspension).
conclusionOverall, in this large retrospective cohort, paracervical block performed through a vaginoscopic approach was associated with reduced pain perception and procedure suspension in selected patients.
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