Evidence map›Paper›PMID 42339479›Full record

ArticleAnimal reproduction2026

Effects of resveratrol supplementation to equine sperm during semen cryopreservation.

Natália de Castro Alves, Marina Morra Freitas, Jade Raquel Dias Farias, Cesar Lopes Horta, José de Oliveira Carvalho, Olindo Assis Martins-Filho, Márcio Sobreira Silva Araújo, Ângela Quintão Lana, Guilherme Mattos Jardim Costa, Fernanda Radicchi Lobato de Almeida and 2 more

Abstract read
In one paragraph

Article in Animal reproduction, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Natália de Castro AlvesEscola de Veterinária, Universidade Federal de Minas Gerais - UFMG, Belo Horizonte, MG, Brasil.ORCID 0000-0002-6460-5856
Marina Morra FreitasEscola de Veterinária, Universidade Federal de Minas Gerais - UFMG, Belo Horizonte, MG, Brasil.ORCID 0000-0002-9742-3426
Jade Raquel Dias FariasEscola de Veterinária, Universidade Federal de Minas Gerais - UFMG, Belo Horizonte, MG, Brasil.ORCID 0000-0003-4355-8939
Cesar Lopes HortaEscola de Veterinária, Universidade Federal de Minas Gerais - UFMG, Belo Horizonte, MG, Brasil.ORCID 0009-0004-5466-2277
José de Oliveira CarvalhoFaculdade de Medicina Veterinária, Universidade Federal do Espírito Santo - UFES, Alegre, ES, Brasil.ORCID 0000-0003-0369-9649
Olindo Assis Martins-FilhoLaboratório de Diagnóstico e Monitoramento de Biomarcadores, Centro de Pesquisa René Rachou, Fundação Oswaldo Cruz - Fiocruz, Belo Horizonte, MG, Brasil.ORCID 0000-0002-5494-4889
Márcio Sobreira Silva AraújoLaboratório de Diagnóstico e Monitoramento de Biomarcadores, Centro de Pesquisa René Rachou, Fundação Oswaldo Cruz - Fiocruz, Belo Horizonte, MG, Brasil.ORCID 0000-0002-7532-3360
Ângela Quintão LanaEscola de Veterinária, Universidade Federal de Minas Gerais - UFMG, Belo Horizonte, MG, Brasil.ORCID 0000-0003-0066-6198
Guilherme Mattos Jardim CostaInstituto de Ciências Biológicas, Universidade Federal de Minas Gerais - UFMG, Belo Horizonte, MG, Brasil.ORCID 0000-0002-2907-7760
Fernanda Radicchi Lobato de AlmeidaInstituto de Ciências Biológicas, Universidade Federal de Minas Gerais - UFMG, Belo Horizonte, MG, Brasil.ORCID 0000-0003-4219-1290
Erica Azevedo CostaEscola de Veterinária, Universidade Federal de Minas Gerais - UFMG, Belo Horizonte, MG, Brasil.ORCID 0000-0002-5396-3818
Monique de Albuquerque LagaresEscola de Veterinária, Universidade Federal de Minas Gerais - UFMG, Belo Horizonte, MG, Brasil.ORCID 0000-0003-1795-6984

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During equine semen cryopreservation, most of the seminal plasma is removed, making sperm more susceptible to oxidative stress. This study evaluated the effect of resveratrol supplementation on the quality of frozen-thawed equine sperm. Semen from ten stallions was frozen using a control INRA 96 extender and extenders supplemented with 5-, 10-, 100-, and 150- µM resveratrol. Post-thaw evaluations included motility, kinematic parameters, morphology, plasma and acrosomal membrane integrity, mitochondrial potential, lipid peroxidation, nitrite, hydrogen peroxide, malondialdehyde levels, total reactive oxygen species (ROS), chromatin protamine deficiency, chromatin condensation, sperm binding to bovine oviduct explants, and gene expression of apoptosis-related genes such as B cell lymphoma 2 (BCL2) and BCL2-associated X (BAX), mitochondrial ROS modulator 1 associated with mitochondrial ROS production (ROMO1), sperm acrosome-associated 3 related with sperm binding capacity to the zona pellucida (SPACA3), and DNA damage repair gene 8-oxoguanine DNA glycosylase 1 (OGG1). Data were analyzed by ANOVA and Tukey test (

Indexed as

antioxidantcryopreservationreproductionsemenstallion

Identifiers

PMID42339479
PMCPMC13286545

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.