ArticleJournal of the Endocrine Society2026
Prevalence of diabetes mellitus in long-term cancer survivors treated with craniospinal irradiation.
Article in Journal of the Endocrine Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Prevalence of diabetes mellitus in long-term cancer survivors treated with craniospinal irradiation.Journal of the Endocrine Society · 2026Article
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Authors and funding
9 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Background: Childhood, adolescent, and young adult cancer survivors (CAYA) are at an increased risk for metabolic disorders such as diabetes mellitus. Although this risk has been well-documented for leukemia survivors and those exposed to abdominal radiotherapy, the metabolic risk profile for brain tumor survivors remains largely unexplored. Methods: This study assessed the prevalence of diabetes and dysglycemia in 2 CAYA survivor cohorts. The first included medulloblastoma and ependymoma survivors (HIT-MED), with data collected via self-reported online questionnaires. The second (CLI) was a retrospective analysis of an unselected cohort from our late effects clinic. In this cohort, dysglycemia was defined using hemoglobin A1c measurements alone, without additional glucose-based diagnostic criteria. Results: In the HIT-MED group, 37% (197/527) participated in an online-based questionnaire, revealing a diabetes mellitus prevalence of 3.05%. A total of 122 were male and 75 female, mean age was 27.1 ± 4.5 years (range 19-41). In comparison to an age-matched general population, there was no significant difference ( Conclusion: CAYA brain tumor survivors exposed to craniospinal radiotherapy have an elevated risk of dysglycemia compared to other survivor cohorts. These findings support the need for structured, risk-adapted long-term metabolic monitoring to enable early intervention and reduce long-term morbidity.
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