ArticleInternational journal of microbiology2026
Emerging Multidrug-Resistant Bacteria in Indonesian Neonatal Patients: Prevalence and Antimicrobial Resistance Profiles From Clinical Samples.
Article in International journal of microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Emerging Multidrug-Resistant Bacteria in Indonesian Neonatal Patients: Prevalence and Antimicrobial Resistance Profiles From Clinical Samples.International journal of microbiology · 2026Article
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7 authors.
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Abstract
Background: Neonatal sepsis poses a serious health challenge, especially with the increasing prevalence of multidrug-resistant (MDR) bacteria among Indonesian neonates. This study examines the occurrence of MDR bacteria in clinical samples from neonates and analyzes their resistance patterns to enhance treatment strategies. Methods: From January 2022 to December 2024, a total of 223 bacterial isolates were gathered from neonatal patients with infections at Kanjeng Raden Mas Tumenggung Wongsonegoro Hospital in Semarang, Indonesia. The identification process commenced with Gram staining and assessment of colony morphology preceded by antibiotic susceptibility testing utilizing the VITEK2 Compact systems. Results: The study findings revealed a notable prevalence of MDR infections. Fecal samples accounted for 29.15% of the samples analyzed, with 63.1% exhibiting MDR characteristics. Blood samples, representing 24.66% of the samples, displayed a concerning MDR rate of 83.6%. Similarly, urine samples (24.66%) showed a MDR rate of 50.9%, while sputum samples (10.76%) presented a striking MDR classification of 91.7%. Key MDR rates were identified in Conclusion: The findings underscore the urgent need for effective strategies to combat MDR infections in healthcare settings, emphasizing enhanced antibiotic management, tailored treatment protocols, and a more holistic and systematically structured research strategy for neonatal units in Indonesia.
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