Evidence map›Paper›PMID 42339179›Full record

ReviewToxicology reports2026

Synthetic biology of oncolytic bacteria: Comparative microbial chassis and precise killing strategies.

Mustafa Attiyah Hadid, Nawfal Haitham Al Shaikhli, Omar Khalid Suhail, Samar T Hameed, Muhtada Ali Challoob

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Toxicology reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mustafa Attiyah HadidApplied Pathological Analysis, College of Science, Al-Nahrain University, Baghdad, Iraq.
Nawfal Haitham Al ShaikhliApplied Pathological Analysis, College of Science, Al-Nahrain University, Baghdad, Iraq.
Omar Khalid SuhailApplied Pathological Analysis, College of Science, Al-Nahrain University, Baghdad, Iraq.
Samar T HameedCollege of Pharmacy, Al-Nahrain University, 60th Street, Northern Complex, Al-Kadhimiya, Baghdad 10006, Iraq.
Muhtada Ali ChalloobCollege of Pharmacy, University of Misan, Maysan, Iraq.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The field of synthetic biology has become a revolutionary tool for engineering microorganisms capable of precise, programmed cancer treatment. Unlike conventional cancer treatments, which lack safe, selective toxicity, engineered microbial cells can detect tumor-specific signals, target hypoxic environments, and deliver cytotoxic payloads more effectively in both space and time. This review presents the most recent advancements in microbial chassis engineering, including

Indexed as

Cytotoxic payloadsGene circuitMicrobial Cancer TherapySynthetic biologyTumor targeting

Identifiers

PMID42339179
PMCPMC13284426

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.