Evidence map›Paper›PMID 42339046›Full record

ArticleCase reports in anesthesiology2026

Anesthetic Management in a Patient With Tethered Spinal Cord Syndrome Undergoing Knee Replacement Surgery.

Lucas Alessi, Adrianne Bonham, Kiera Wendell, Jackson Eisenhauer, Saba Bolbolan, Elena Reshetnikoff, Richard Alessi, Matthew McEchron

Abstract read
In one paragraph

Article in Case reports in anesthesiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lucas AlessiOMS IV College of Osteopathic Medicine, Rocky Vista University, Parker, Colorado, USA, rvu.edu.ORCID https://orcid.org/0009-0004-5375-6239
Adrianne BonhamOMS IV College of Osteopathic Medicine, Rocky Vista University, Parker, Colorado, USA, rvu.edu.ORCID https://orcid.org/0009-0005-4013-2141
Kiera WendellOMS IV College of Osteopathic Medicine, Rocky Vista University, Parker, Colorado, USA, rvu.edu.ORCID https://orcid.org/0009-0004-8010-181X
Jackson EisenhauerOMS IV College of Osteopathic Medicine, Rocky Vista University, Parker, Colorado, USA, rvu.edu.ORCID https://orcid.org/0009-0003-3150-3938
Saba BolbolanOMS IV College of Osteopathic Medicine, Rocky Vista University, Parker, Colorado, USA, rvu.edu.ORCID https://orcid.org/0009-0000-3266-3931
Elena ReshetnikoffOMS IV College of Osteopathic Medicine, Rocky Vista University, Parker, Colorado, USA, rvu.edu.ORCID https://orcid.org/0009-0003-7846-266X
Richard AlessiNorthern Colorado Anesthesia Professionals, Fort Collins, Colorado, USA.
Matthew McEchronRocky Vista University College of Osteopathic Medicine, Parker, Colorado, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tethered spinal cord syndrome (TSCS) is a neurological disorder characterized by tissue attachments limiting spinal cord movement, which can result in the conus medullaris terminating at a level lower than the typical L1. This abnormality can cause significant complications during spinal anesthesia due to the risk of injury at the traditional puncture sites of L4-L5. This case report discusses the anesthetic management of a 65-year-old female patient diagnosed with TSCS with her spinal cord extending to L5-S1. She presented for a right total knee replacement. The patient had a history of successful spinal anesthesia for her previous left knee replacement but was apprehensive about repeating the procedure due to her spinal anatomy and the associated risks. A thorough preoperative assessment was conducted with this patient. This included a detailed MRI review by a radiologist and a neurosurgeon, which highlighted the risks associated with spinal anesthesia. Given the minimal cerebrospinal fluid around critical levels of the spinal cord, the risk of injury during spinal anesthesia was significant. After discussion with the patient about the risks and benefits of each anesthetic option, the care team and patient jointly decided that general anesthesia would offer the safest approach. General anesthesia was administered successfully with standard intraoperative monitoring and airway management. A preoperative adductor nerve block was also performed to manage postoperative knee pain. The patient emerged from anesthesia without complications, with stable vital signs and good neurovascular function. The interdisciplinary approach and careful preoperative planning were crucial to achieve a positive outcome in this case. This case highlights the importance of individualized anesthetic planning for patients with TSCS. It underscores the need for thorough preoperative assessment and patient-centered care to determine the safest anesthetic approach. This report also reviews the mechanisms of spinal cord injury during neuraxial anesthesia in TSCS, discusses epidural anesthesia as an alternative, and synthesizes evidence-based recommendations for preoperative assessment in the absence of formal guidelines. Further research and the development of formal guidelines for anesthetic management in TSCS are warranted to improve patient safety and outcomes.

Indexed as

anesthetic managementcerebrospinal fluidconus medullarisgeneral anesthesialumbar spine MRIspinal anesthesiatethered cord syndrometotal knee replacement

Identifiers

PMID42339046
PMCPMC13284101

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